Important issues on the prevention of surgical site infections and the management of prophylactic antibiotics  

作　　者：Xue-Lu Yu Jian-Hui Peng Qing Chang Jing-Wen Chen Ji-Shun Yang Ming-Ke Wang 

机构地区：[1]Naval Medical Center of People’s Liberation Army,Naval Medical University,Shanghai 200052,China [2]Department of Quality Management,Guangdong Second Provincial General Hospital,Guangzhou 510317,Guangdong Province,China [3]The Third Department of Convalescence,Beidaihe Rehabilitation and Convalescence Center of People’s Liberation Army,Qinhuangdao 066000,Hebei Province,China [4]School of Pharmacy,Bengbu Medical University,Bengbu 233000,Anhui Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2025年第4期428-434,共7页世界胃肠外科杂志(英文)

基　　金：Supported by Scientific Research Foundation of Shanghai Municipal Health Commission of Changning District,No.20234Y038;Medical Science and Technology Research Foundation of Guangdong Province,China,No.C2022023.

摘　　要：In this article, we have addressed the recent published article by Wang et al whichexamines risk factors associated with surgical site infections (SSIs) and evaluatesthe effectiveness of prophylactic antibiotics in their prevention. Wang et al identifiedseveral significant risk factors of SSIs, including age ≥ 60 years, diabetesmellitus, and surgical complications such as insufficient cystic duct stump closure,gallbladder perforation, empyema, and postoperative hematoma. Their findingssuggest that prophylactic antibiotics can serve as a protective factor against SSIs.However, other reported risk factors and preventive strategies warrant considerationto further reduce the incidence of SSIs, lower healthcare costs, and enhancepatient outcomes. Additionally, the judicious use of prophylactic antibioticsis crucial in light of the growing global challenge of antibiotic resistance caused bythe misuse and overuse of antibiotics. Effective management strategies forprophylactic antibiotic use should be prioritized to balance infection control withthe need to combat antimicrobial resistance.

关 键 词：Surgical site infections Prophylactic antibiotics Risk factors Preventive measures MANAGEMENT 

分 类 号：R57[医药卫生—消化系统]