腹膜透析患者发生相关性腹膜炎的影响因素  

Influencing factors of peritonitis in peritoneal dialysis patients

作　　者：李宇慧 郑梓晴 LI Yuhui;ZHENG Ziqing(Department of Nephrology,the First Affiliated Hospital of Xiamen University,Fujian Province,Xiamen 361000,China)

机构地区：[1]厦门大学附属第一医院肾内科,福建厦门361000

出　　处：《中国当代医药》2025年第8期122-125,共4页China Modern Medicine

摘　　要：目的探讨腹膜透析患者发生相关性腹膜炎的影响因素。方法回顾性分析2021年1月至2023年12月厦门大学附属第一医院接受腹膜透析治疗的160例患者的临床资料,按照是否出现腹膜透析相关性腹膜炎分为腹膜炎组(n=26)与非腹膜炎组(n=134),先后采用单因素以及多因素logistic回归分析探讨腹膜透析相关性腹膜炎的影响因素。结果单因素分析结果显示,腹膜炎组的年龄高于非腹膜炎组,体重指数(BMI)低于非腹膜炎组,有感染史患者比例高于非腹膜炎组,透析时间长于非腹膜炎组,差异有统计学意义(P<0.05)。两组患者的性别、合并糖尿病、合并高血压、透析液类型比较,差异无统计学意义(P>0.05)。多因素logistic回归分析结果显示,年龄(β=0.210,OR=1.234,95%CI:1.050~1.450)、透析时间(β=0.456,OR=1.578,95%CI:1.083~2.299)、感染史(β=1.789,OR=5.978,95%CI:1.238~28.877)是腹膜透析相关性腹膜炎的独立危险因素(P<0.05);BMI(β=-0.260,OR=0.771,95%CI:0.619~0.961)为腹膜透析相关性腹膜炎的独立保护因素(P<0.05)。结论年龄、透析时间、感染病史、BMI为腹膜透析相关性腹膜炎发生的独立影响因素,在临床工作中需要引起临床工作者的充分重视。Objective To investigate the influencing factors of peritonitis in peritoneal dialysis patients.Methods The clinical data of 160 patients who received peritoneal dialysis treatment in the First Affiliated Hospital of Xiamen University from January 2021 to December 2023 were retrospectively analyzed.They were divided into peritonitis group(n=26)and non-peritonitis group(n=134)according to whether they had peritoneal dialysis-associated peritonitis.The influencing factors of peritoneal dialysis-associated peritonitis were investigated by univariate and multivariate logistic regression analysis.Results Univariate analysis showed that the age of the peritonitis group was higher than that of the non-peritonitis group,the body mass index(BMI)was lower than that of the non-peritonitis group,the proportion of patients with history of infection was higher than that of the non-peritonitis group,and the dialysis time was longer than that of the non-peritonitis group,with statistical significances(P<0.05).There were no significant differences in gender,diabetes mellitus,hypertension and dialysate type between the two groups(P>0.05).Multivariate logistic regression analysis showed that age(β=0.210,OR=1.234,95%CI:1.050-1.450),dialysis time(β=0.456,OR=1.578,95%CI:1.083-2.299)and infection history(β=1.789,OR=5.978,95%CI:1.238-28.877)were independent risk factors for peritoneal dialisation-associated peritonitis(P<0.05).BMI(β=-0.260,OR=0.771,95%CI:0.619-0.961)was independent protective factor for peritoneal dialysis-associated peritonitis(P<0.05).Conclusion Age,dialysis time,infection history and BMI are independent influencing factors of peritoneal dialysis-associated peritonitis,which should be paid attention by clinical workers.

关 键 词：腹膜透析 透析时间 营养 感染 腹膜透析相关性腹膜炎 影响因素 

分 类 号：R572.2[医药卫生—消化系统]