牙周辅助加速成骨正畸治疗的研究进展  

Research progress in periodontally accelerated osteogenic orthodontics

作　　者：熊奕宸 陈珺[1,2] 李文杰[1,3] XIONG Yichen;CHEN Jun;LI Wenjie(Xiangya School of Stomatology,Central South University,Hunan Engineering Research Center for Oral Digitizatize and Personalize Diagnostic and Therapeutic Technology,Hunan Key Laboratory of Oral Health Research,Hunan Clinical Research Center of Oral Major Diseases and Oral Health,Academician Wang Songling Expert Workstation of Oral and Maxillofacial Regeneration,Changsha 410078;Department of Periodontics,Xiangya Stomatological Hospital,Central South University,Changsha 410078;Department of Orthodontics,Xiangya Stomatological Hospital,Central South University,Changsha 410078,China)

机构地区：[1]中南大学湘雅口腔医学院,口腔数智化与个体化诊疗技术湖南省工程研究中心,口腔健康研究湖南省重点实验室,湖南省口腔重大疾病与口腔健康临床医学研究中心,口腔颌面再生王松灵院士专家工作站,长沙410078 [2]中南大学湘雅口腔医院牙周科,长沙410078 [3]中南大学湘雅口腔医院正畸科,长沙410078

出　　处：《中南大学学报(医学版)》2024年第12期2005-2015,共11页Journal of Central South University :Medical Science

基　　金：湖南省临床医疗技术创新引导项目(2021SK53602);中南大学湘雅口腔医院医疗新技术新业务项目(2023JS01,2023JS04)。

摘　　要：牙周辅助加速成骨正畸治疗(periodontally accelerated osteogenic orthodontics,PAOO)是正畸治疗的辅助手段,其基础原理为“局部加速现象”,即通过促进破骨细胞的活动达到加速正畸治疗的目的。在临床应用上,其手术方法近年来逐步优化,包括压电骨皮质切开术、牙槽骨微穿孔术等新术式的应用。所使用的材料也逐渐改良,包括生物活性玻璃等新型移植材料和富血小板纤维蛋白膜等新型屏障膜。正是由于这些临床创新的涌现,PAOO正朝着低痛苦、低损伤、高疗效的方向发展。但是,目前关于PAOO的临床研究尚少,未来仍需大样本、多中心的随机对照试验来评价不同术式、不同植骨材料等对PAOO临床疗效的影响。Periodontally accelerated osteogenic orthodontics(PAOO)is an adjunctive technique in orthodontic treatment,based on the principle of the regional acceleratory phenomenon(RAP).It aims to shorten orthodontic treatment duration by enhancing osteoclast activity.In recent years,the surgical approach of PAOO has been gradually optimized with the development of techniques such as piezosurgical corticotomy and alveolar micro osteoperforations.The materials used have also improved,including novel grafting materials such as bioactive glass and new barrier membranes like platelet-rich fibrin.Thanks to these clinical innovations,PAOO is evolving toward a trend of minimal pain,low invasiveness,and high efficacy.However,clinical research on PAOO remains limited,large-sample,multicenter randomized controlled trials are still needed to evaluate the clinical effectiveness of different surgical techniques and grafting materials in PAOO.

关 键 词：牙周辅助加速成骨正畸治疗 局部加速现象 骨皮质切开 正畸牙齿移动 牙槽骨骨量 

分 类 号：R78[医药卫生—口腔医学]