超声联合血液学检验诊断急性复杂性阑尾炎  

Ultrasound combined with hematologic tests for diagnosing acute complicated appendicitis

作　　者：陈梅华 林青青 林碧霞 谢美香 黄文君 CHEN Meihua;LIN Qingqing;LIN Bixia;XIE Meixiang;HUANG Wenjun(Department of Ultrasound,the First Hospital of Putian City,Putian 351100,China;Department of Ultrasound,the First Affiliated Hospital of Fujian Medical University,Fuzhou 350005,China)

机构地区：[1]莆田市第一医院超声医学科,福建莆田351100 [2]福建医科大学附属第一医院超声医学科,福建福州350005

出　　处：《中国医学影像技术》2025年第3期477-481,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的观察超声联合血液学检验诊断急性复杂性阑尾炎的价值。方法回顾性分析225例急性阑尾炎患者资料,根据术中所见及术后病理将其分为急性复杂性阑尾炎组(复杂组,n=33)与急性非复杂性阑尾炎组(非复杂组,n=192);比较2组临床资料、术前血液学检验及超声所见。采用多因素logistic回归分析构建诊断急性复杂性阑尾炎的联合模型,以受试者工作特征(ROC)曲线下面积(AUC)评价单一各因素及其联合诊断急性复杂性阑尾炎的价值,并以DeLong检验进行比较。结果相比非复杂组,复杂组患者年龄较高,发热、呕吐者更多,C反应蛋白(CRP)及中性粒细胞与淋巴细胞比值(NLR)水平更高,阑尾外径更大,伴阑尾腔内粪石及阑尾周围脓肿者占比更高(P均<0.05)。多因素logistic回归分析显示,血清CRP、NLR升高,以及超声显示阑尾外径增大、阑尾周围脓肿均为急性复杂性阑尾炎的独立预测因素(P均<0.05);据此建立的logistic回归模型诊断急性复杂性阑尾炎的效能(AUC=0.854)高于各单一指标(Z=2.548~4.527,P均<0.05)。结论超声联合血清CRP及NLR诊断急性复杂性阑尾炎具有较高价值。Objective To observe the value of ultrasound combined with hematologic tests for diagnosing acute complicated appendicitis.Methods Data of 225 patients with acute appendicitis confirmed by surgery and postoperative pathology were retrospectively analyzed.The patients were divided into acute complicated appendicitis group(complicated group,n=33)and acute uncomplicated appendicitis group(uncomplicated group,n=192)based on operational and post operation pathological findings.Clinical data,hematologic test results and ultrasound findings before operation were compared between groups.Multivariate logistic regression was used to construct a combination model for diagnosing acute complicated appendicitis.Receiver operating characteristic(ROC)curve and area under the curve(AUC)were used to evaluate the diagnostic value of predictive factor alone and their combination for diagnosing acute complicated appendicitis,which were then compared with DeLong test.Results Compared with uncomplicated group,patients in complicated group were older,with higher proportion of fever and vomiting,higher level of C reactive protein(CRP)and of neutrophil-to-lymphocyte ratio(NLR),larger external diameters of appendix,also higher proportion of appendiceal intracavitary fecalith and periappendiceal abscess(all P<0.05).Multivariate logistic regression analysis showed that elevated serum CRP and NLR,increased external diameter of appendix and periappendiceal abscess were all predictive factors of acute complicated appendicitis(all P<0.05).The diagnostic efficiency of logistic regression model constructed based on the above factors(AUC=0.854)was higher than that of each single predictive factor alone(Z=2.548-4.527,all P<0.05).Conclusion Ultrasound combined with hematologic tests had high value for diagnosing acute complicated appendicitis.

关 键 词：阑尾炎 超声检查 血液学试验 诊断 鉴别 

分 类 号：R574.61[医药卫生—消化系统] R445.1[医药卫生—内科学]