多层螺旋CT三期增强扫描对肺癌化疗疗效及近期预后的评估  

Evaluation of Three Phase Enhanced Multi-Slice Spiral CT Scanning for Chemotherapy Efficacy and Recent Prognosis in Lung Cancer

作　　者：赵美东 周海波 ZHAO Mei-dong;ZHOU Hai-bo(Department of Imaging,Gushi County Traditional Chinese Medicine Hospital,Xinyang 465200,China)

机构地区：[1]固始县中医院影像科,信阳465200

出　　处：《四川解剖学杂志》2024年第6期72-75,共4页Sichuan Journal of Anatomy

摘　　要：目的:探讨多层螺旋CT(MSCT)三期增强扫描对肺癌化疗疗效及近期预后的评估价值.方法:选取2020年1月至2021年5月本院收治的80例肺癌患者作为研究对象,所有患者入院时均接受MSCT三期增强扫描检查.化疗3个周期后评估疗效,分析MSCT各参数对化疗疗效的评估价值.患者化疗结束,接受24个月随访,以病死(预后不良)作为随访终点事件,重点分析MSCT三期增强扫描参数对预后的评估价值.结果:化疗3个周期后,有效45例,无效35例;无效组患者各期血流量(BF)值均高于有效组,差异有统计学意义(P<0.05);绘制受试者工作特征曲线(ROC)结果显示,肺癌患者扫描参数单独及联合评估化疗疗效的曲线下面积(AUC)均>0.750.80例患者经24个月随访,病死59例;病死组各期BF值高于生存组,差异有统计学意义(P<0.05);绘制ROC结果显示,肺癌患者各期BF值单独及联合评估预后的AUC均>0.750.结论:MSCT三期增强扫描可用于评估肺癌患者化疗疗效及预后风险.Objective:To explore the evaluation value of three phase enhanced multi-slice spiral CT(MSCT)in the chemotherapy efficacy and recent prognosis of lung cancer.Methods:Eighty lung cancer patients admitted to our hospital from January 2020 to May 2021 were selected as the research subjects.The patients underwent MSCT three-phase enhanced scanning upon admission.The efficacy was evaluated after 3 cycles of chemotherapy,and the evaluation value of MSCT parameters on the efficacy of chemotherapy was analyzed.The patient completed chemotherapy and underwent 24 months follow-up,with mortality(poor prognosis)as the endpoint event.The focus was on analyzing the prognostic value of MSCT phaseⅢenhanced scanning parameters.Results:After 3 cycles of chemotherapy,45 cases were effective and 35 cases were ineffective;The blood flow(BF)values of each period in ineffective group were higher than those in effective group,the differences were statistically significant(P<0.05).The receiver operating characteristic(ROC)curve showed that the area under the curve(AUC)of both individual and combined evaluation of chemotherapy efficacy for lung cancer patients with scanning parameters was greater than 0.750.Eighty patients were followed up for 24 months,with 59 deaths.The BF values of death group were higher than those of survival group,and the differences were statistically significant(P<0.05).The ROC curve was drawn,and the AUC values of individual and combined evaluation of prognosis for lung cancer patients at each stage were all greater than 0.750.Conclusion:MSCT three-phase enhanced scanning can be used to evaluate the chemotherapy efficacy and prognostic risk in lung cancer patients.

关 键 词：肺癌 多层螺旋CT 疗效 预后 

分 类 号：R73[医药卫生—肿瘤]