文献计量学视角下有关化疗损伤性卵巢早衰的研究现状与趋势  

Current status and trends in research on chemotherapy-induced premature ovarian failure from a bibliometric perspective

作　　者：王雨杭 呼学敏 杜雪 WANG Yuhang;HU Xuemin;DU Xue(Graduate School,Tianjin Medical University,Tianjin 300070,P.R.China;Department of Gynecology,Tianjin Union Medical Center,Nankai University,Tianjin 300121,P.R.China)

机构地区：[1]天津医科大学研究生院,天津300070 [2]天津市人民医院/南开大学第一附属医院妇科,天津300121

出　　处：《华西医学》2025年第3期439-446,共8页West China Medical Journal

摘　　要：目的通过文献计量学方法,深入分析化疗损伤性卵巢早衰领域的研究进展与现状,为科研人员提供科学高效的研究路径。方法检索Web of Science核心合集中2015年—2024年有关化疗损伤性卵巢早衰的全部文献。利用CiteSpace和VOSviewer软件对作者、机构、关键词、共被引文献等进行文献计量分析,绘制关系型图谱。结果共纳入文献567篇,年度科研产出略有增长,中国研究者发文量居于首位。49个筛选后的关键词被分为11个聚类,突现关键词显示,近年的研究热点集中在更深入的机制研究如原发性卵巢功能不全、绝经期前患者生育力保存等,并可能继续作为研究热点。结论近年来化疗损伤性卵巢早衰的研究热度不断攀升,我国学者贡献突出,需进一步加强我国科研工作者的科研合作;生育力保存、激素替代疗法、体外移植等可能成为未来的研究热点,应在多中心、多学科交叉的基础上,进一步推动研究深度化和精细化。Objective To analyze the research progress and current situation in the field of chemotherapyinduced premature ovarian failure by bibliometrics,so as to provide scientific and efficient research path for researchers.Methods All the literature on chemotherapy-induced premature ovarian failure from 2015 to 2024 was retrieved from the Web of Science Core Collection.CiteSpace and VOSviewer software were used to conduct bibliometric analyses of authors,institutions,keywords,co-cited documents,etc.,and to draw the relational graphs.Results A total of 567 papers were included.The annual research output increased slightly,and the number of papers published by Chinese researchers ranked first.The 49 selected keywords were divided into 11 clusters,and the emerging keywords showed that the research hotspots in recent years focused on more in-depth mechanism studies,such as primary ovarian insufficiency and fertility preservation in premenopausal patients,which might continue to be research hotspots.Conclusions In recent years,the research heat of chemotherapy-induced premature ovarian failure has been increasing,and Chinese scholars have made outstanding contributions,however,it is necessary to further strengthen the scientific research cooperation among researchers.Fertility preservation,hormone replacement therapy,in vitro transplantation may become the hotspots of future research,and the depth and refinement of research should be further promoted on the basis of multi-center and multi-disciplinary cross.

关 键 词：文献计量学 化疗损伤性卵巢早衰 可视化图谱 

分 类 号：R73[医药卫生—肿瘤]