大肠埃希菌氨基酸脱羧酶系统耐酸胁迫应答机制研究进展  

Research progress of acid stress response mechanism of amino acid decarboxylase system in Escherichia coli

作　　者：彭玉倩 黄颖 杜昕颖 向莹 邱少富 PENG Yuqian;HUANG Ying;DU Xinying;XIANG Ying;QIU Shaofu(College of Public Health,Zhengzhou University,He’nan Zhengzhou 450001,China;The Centre of Disease Control and Prevention of Chinese People’s Liberation Army,Beijing 100071,China)

机构地区：[1]郑州大学公共卫生学院,河南郑州450001 [2]中国人民解放军疾病预防控制中心,北京100071

出　　处：《中国食品卫生杂志》2024年第12期1394-1400,共7页Chinese Journal of Food Hygiene

基　　金：国家自然科学基金(82202538、82173580)。

摘　　要：食源性致病菌对低pH环境的抗性通常被认为是一个重要的致病决定因素,它帮助细菌通过胃内,并能以极低的感染剂量引起疾病。本文主要围绕大肠埃希菌的3种主要氨基酸脱羧酶系统(谷氨酸脱羧酶系统、精氨酸脱羧酶系统和赖氨酸脱羧酶系统)的耐酸胁迫应答机制的研究进展进行概述,以更清晰地展示食源性致病菌的耐酸机制。Resistance of foodborne pathogens to low pH environments is often considered one of important determinant of disease,which helps bacteria pass through the stomach and can cause illness at very low infective doses.The research progress of three major amino acid decarboxylase systems in Escherichia coli,namely glutamic acid decarboxylase system,arginine decarboxylase system and lysine decarboxylase system were summarized.The primary objective is to elucidate the acid-resistant mechanism of foodborne pathogens.

关 键 词：大肠埃希菌 谷氨酸脱羧酶系统 精氨酸脱羧酶系统 赖氨酸脱羧酶系统 

分 类 号：R155[医药卫生—营养与食品卫生学]