Raman spectroscopy in the diagnosis of malignant biliary stricture:A feasibility study  

作　　者：Peter Slodicka Premysl Falt Václav Ranc Vincent Dansou Zoundjiekpon Ondrej Urban 

机构地区：[1]2nd Department of Internal Medicine-Gastroenterology and Geriatrics,University Hospital Olomouc,Olomouc,Czech Republic [2]Faculty of Medicine and Dentistry,Palacky University,Olomouc,Czech Republic [3]Institute of Molecular and Translational Medicine,Faculty of Medicine,Palacky University,Olomouc,Czech Republic

出　　处：《Hepatobiliary & Pancreatic Diseases International》2025年第2期211-216,共6页国际肝胆胰疾病杂志(英文版)

基　　金：supported by a grant from MH CZ–DRO(FNOl,00098892)。

摘　　要：Biliary strictures are caused by both benign and malignant pathologies.Although up to 30%of biliary strictures are identified as benign,the vast majority are malignant with two major malignancies,namely pancreatic adenocarcinoma and cholangiocarcinoma(CC)[1].Accurate diagnosis and precise localization play a vital role in the prognosis and management of the disease[2].In this study we primarily focused on the diagnosis of CC.The highest incidence of CC is in northeastern Thailand,where the incidence is found to be 100/100000 in males and 50/100000 in females.In Western countries,it is approximately(0.5–2.0)/100000 individuals[3].CC is most often diagnosed between the ages of 70 and 80 years[4].The prognosis of biliary malignancies is dismal with overall five-year survival as low as 10%[5].

关 键 词：DIAGNOSIS MALIGNANT STRICTURE 

分 类 号：R735.8[医药卫生—肿瘤]