子宫-膀胱间隙异位副神经节瘤诊治一例  

Diagnosis and Treatment of Paraganglioma in Utero-Bladder Space:A Case Report

作　　者：潘如[1] 陈紫均 杨海坤[1] 余祝英 吴生盛 PAN Ru;CHEN Zijun;YANG Hai-kun;YU Zhu-ying;WU Sheng-sheng(Department of Gynecology,Meizhou People′s Hospital,Meizhou 514000,Guangdong Province,China)

机构地区：[1]广东省梅州市人民医院妇科,514000

出　　处：《国际生殖健康/计划生育杂志》2025年第2期128-131,共4页Journal of International Reproductive Health/Family Planning

基　　金：广东省基础与应用基础研究基金省企联合基金(面上项目)(2023A1515220157)。

摘　　要：副神经节瘤(paraganglioma,PGL)是源自肾上腺外嗜铬细胞的罕见肿瘤,而发生部位在子宫-膀胱间隙且术前无任何症状的相关病例更为鲜见。报道1例罕见的PGL病例,术前无头痛、出汗、高血压及心动过速等典型PGL症状。术中见肿瘤位于子宫与膀胱间隙中,触碰肿瘤时出现血压异常波动、血氧下降、室颤、房颤等心律失常,在术中稳定生命体征后进行了全子宫+双侧附件切除术,术后转重症监护病房密切监测生命体征,予以对症治疗后患者痊愈出院,出院时血压、心功能稳定,无并发症,术后2个月复查儿茶酚胺、血压、妇科彩色超声等无明显异常。通过该病例的临床特点和辅助检查情况,分析术前精确诊断要点,以降低PGL的围手术期风险,提高患者生存率。Paraganglioma(PGL)is a rare tumor derived from extra-adrenal chromaffin cells.The occurrence of PGL in utero-bladder space without any symptoms before surgery is more rare.We report a rare case of ectopic pheochromocytoma without typical symptoms of headache,sweating,hypertension,and tachycardia.During the operation,we found that the tumor was located in the space between uterus and bladder,and that abnormal fluctuation of blood pressure,decrease of blood oxygen,ventricular fibrillation,atrial fibrillation and other arrhythmias occurred when touching the tumor.After stabilizing vital signs during the operation,the whole uterus plus bilateral adnexectomy was performed.After operation,the patient was transferred to ICU for close examination of vital signs,and was discharged after symptomatic treatment.The patient was cured and discharged from the hospital with stable blood pressure and cardiac function without complications.No abnormality was found in the reexamination of two months after the operation,including catecholamine,blood pressure and gynecological color ultrasound.By sorting out the clinical characteristics and auxiliary examination of this case,we analyzed the key points of preoperative diagnosis to reduce the perioperative risk of PGL and improve survival rate.

关 键 词：副神经节瘤 儿茶酚胺类 诊断 治疗 病例报告 

分 类 号：R737.14[医药卫生—肿瘤] R737.33[医药卫生—临床医学]