介入治疗在胃肠道恶性肿瘤肝转移瘤患者中的应用效果观察  

Clinical Observation on the Application of Interventional Therapy in Patients with Liver Metastases from Gastrointestinal Malignant Tumors

作　　者：裴鹏昌 顾智文 黎年初 卢东 李家曾 PEI Pengchang;GU Zhiwen;LI Nianchu;LU Dong;LI Jiazeng(The Eighth People's Hospital of Nanning,Nanning 530000,China)

机构地区：[1]南宁市第八人民医院,广西南宁530000

出　　处：《延边大学医学学报》2025年第2期65-67,共3页Journal of Medical Science Yanbian University

摘　　要：目的:探讨介入治疗在胃肠道恶性肿瘤肝转移瘤患者中的应用效果。方法:研究选取56例胃肠道恶性肿瘤肝转移患者,均来自南宁市第八人民医院,随机分成观察组(采用介入治疗)和对照组(采用常规化疗),每组28例。比较两组的临床治疗效果。结果:观察组近期疗效显著优于对照组,治疗有效率为71.4%,临床控制率为100.0%,均显著高于对照组的28.6%和71.4%(P<0.05)。观察组血清肿瘤标志物多项指标水平及不良反应发生率均低于对照组,差异显著(P<0.05)。结论:介入治疗在胃肠道恶性肿瘤肝转移瘤患者中的应用效果显著,优于常规化疗,值得在临床中推广应用。Objective:To investigate the clinical efficacy of interventional therapy in patients with liver metastases from gastrointestinal malignant tumors.Methods:A total of 56 patients with liver metastases from gastrointestinal malignancies,admitted to The Eighth People's Hospital of Nanning,were randomly divided into an observation group(interventional therapy,n=28)and a control group(conventional chemotherapy,n=28).Clinical outcomes were compared between the two groups.Results:The short-term efficacy of the observation group was significantly superior to that of the control group.The treatment response rate was 71.4%in the observation group,and the clinical control rate reached 100.0%,both significantly higher than the control group's 28.6%and 71.4%(P<0.05).Additionally,the observation group demonstrated significantly lower levels of multiple serum tumor markers and a reduced incidence of adverse reactions compared to the control group(P<0.05).Conclusion:Interventional therapy exhibits superior clinical efficacy over conventional chemotherapy in managing liver metastases from gastrointestinal malignancies,with favorable safety profiles.It is worthy of broader clinical application.

关 键 词：胃肠道恶性肿瘤 肝转移瘤 介入治疗 肿瘤标志物 不良反应 

分 类 号：R73[医药卫生—肿瘤]