The Role of Glutathione S-Transferase in the Regulation of Plant Growth, and Responses to Environmental Stresses  

作　　者：Chen Lin Zidan Zhang Zhao Zhang Yuxiang Long Xuwen Shen Jinghao Zhang Youping Wang 

机构地区：[1]Key Laboratory of Plant Functional Genomics of the Ministry of Education,Yangzhou University,Yangzhou,225009,China [2]Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding,Yangzhou University,Yangzhou,225009,China

出　　处：《Phyton-International Journal of Experimental Botany》2025年第3期583-601,共19页国际实验植物学杂志(英文)

基　　金：funded by National Natural Science Foundation of China(grant no.32301870 to Chen Lin);Natural Science Foundation of Jiangsu Province(grant no.BK20230568 to Chen Lin);the Jiangsu Provincial Agricultural Science and Technology Independent Innovation Fund(grant no.CX(24)3124 to Chen Lin);Outstanding Ph.D.Programin Yangzhou(grant no.YZLYJFJH2022YXBS147 to Chen Lin);the General Project of Basic Scientific Research to colleges and universities in Jiangsu Province(grant no.22KJB210019 toChen Lin);the Priority Academic Program Development of Jiangsu Higher Education Institutions is greatly acknowledged.

摘　　要：Glutathione S-transferases (GSTs) represent a large and diverse enzyme family ubiquitously distributed across the plant kingdom. These proteins catalyze the conjugation of glutathione (GSH) with electrophilic substrates in response to various stress conditions. Beyond their role in stress adaptation, certain GSTs are integral regulators of plant growth and development, contributing to a range of physiological processes. Most GST proteins exhibit dual enzymatic activities, functioning as both transferases and peroxidases, which enables their involvement in diverse cellular processes, including detoxification and stress responses. Recent advancements, particularly in X-ray crystallography, have enabled detailed structural analysis of GST proteins, significantly enhancing our understanding of their biological functions. This review offers a comprehensive overview of the classification and structural characteristics of GSTs in plants. It also highlights recent findings on their roles in plant growth and development, cell signaling, catalytic transport, and stress tolerance. Furthermore, key scientific challenges related to GSTs are discussed, focusing on their potential applications in agriculture. These insights aim to facilitate the screening of functional GST genes and support molecular breeding efforts across diverse crop species.

关 键 词：Glutathione S-transferase biotic and abiotic stress plant growth and development signal transduction biological functions 

分 类 号：R73[医药卫生—肿瘤]