青年女性乳腺浸润性导管癌临床和超声特征分析  

Clinical and ultrasonic characteristics of invasive ductal carcinoma of breast in young women

作　　者：邢晶波 郑霞 庞坤坤 张飞雪[1] 魏修良 XING Jing-bo;ZHENG Xia;PANG Kun-kun;ZHANG Fei-xue;WEI Xiu-liang(Department of Ultrasound,the Second Hospital of Shandong University,Jinan 250033,China;Department of Emergency,the People’s Hospital of Qihe County,Dezhou 251100,China)

机构地区：[1]山东大学第二医院医学影像中心超声科,山东济南250033 [2]齐河县人民医院急诊科,山东德州251100

出　　处：《中国现代普通外科进展》2025年第3期203-207,共5页Chinese Journal of Current Advances in General Surgery

摘　　要：目的:分析青年女性乳腺浸润性导管癌(IDC)的临床及超声特征,提高青年女性乳腺IDC的超声诊断正确率。方法:回顾性分析2015年12月—2023年6月于山东大学第二医院手术的女性IDC患者的临床资料,收集其临床信息、术前超声特征及术后病理结果等。根据年龄分为两组,≤35岁为青年组,>35岁为对照组,利用单因素t检验、多因素Logistic回归分析评估两组间特征差异。结果:超声诊断正确率(青年组81%,对照组94%),两组差异有统计学意义(χ^(2)=13.082,P=0.001);对比对照组,青年组病史较短,多发病变比例、病变后方回声改变比例及乏血供病变比例均较高(P<0.05);而在乳腺癌家族史、其他肿瘤家族史、临床症状、病变大小、病变分型、触诊、位置、纵横比、病变回声、形态、边缘表现、亮环征、钙化特点、雌激素受体、孕激素受体、人表皮生长因子受体-2及Ki67等方面差异均无统计学意义(P>0.05)。结论:青年女性乳腺IDC的发病率较低,超声误诊率偏高,当病史较短、病变多发、病变后方回声改变及内部乏血供时应考虑到IDC可能性,特别是后方回声衰减或增强时更要高度重视。Objective:To analyze the clinical and ultrasonic features of breast invasive ductal carcinoma in young women patients,and improve the accuracy of ultrasonic diagnosis of breast invasive ductal carcinoma in young patients.Methods:A retrospective study was conducted on patients with invasive ductal carcinoma who underwent surgery in the Second Hospital of Shandong University from December 2015 to June 2023,with complete clinical data,preopera-tive ultrasonography and postoperative pathology.All patients were divided into two groups:young group(≤35 year-old)and control group(>35 year-old).Univariate t-test and multivariate Logistic regression analyses were used to assess the factors.Results:There was a statistical difference between the young group and the control group in the accuracy of ultrasound diagnosis(young group 81%vs control group 94%,χ^(2)=13.082,P=0.001).Compared with the control group,the young group had a shorter disease history,a higher proportion of multiple masses,posterior echo changes and hypo-vascular lesions(P<0.05).However,there was no statistical difference in family history of breast cancer,other cancer family history,clinical symptoms,size,lesion classification,palpation,location,aspect ratio,focus echo,shape,edge per-formance,bright ring sign,calcification characteristics,ER,PR,HER-2 and Ki67(P>0.05).Conclusion:The incidence rate of young breast IDC is low,while the misdiagnosis rate of ultrasound is relatively high.More attention should be paid when the patient has a short history,multiple masses,changes in the posterior echo and less lesion blood supply.

关 键 词：乳腺浸润性导管癌 青年女性 超声检查 临床特征 诊断 

分 类 号：R737.9[医药卫生—肿瘤]