基于火热论分阶段治疗鳞状细胞癌  

Stage Treatment of Squamous Cell Carcinoma Based on the Theory of Fire and Heat

作　　者：马心怡 曹璐畅 王新苗 朱广辉 李杰[1] MA Xinyi;CAO Luchang;WANG Xinmiao;ZHU Guanghui;LI Jie(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing,100053)

机构地区：[1]中国中医科学院广安门医院,北京市西城区100053

出　　处：《中医杂志》2025年第6期569-574,共6页Journal of Traditional Chinese Medicine

基　　金：国家重点研发计划(2023YFC3503300);中央高水平中医医院临床研究和成果转化能力提升项目(HLCMHPP2023085,HLCMHPP2023001,HLCMHPP2023097);中国中医科学院基本科研业务费(ZZ17-XRZ-026)。

摘　　要：认为鳞状细胞癌(简称鳞癌)的发生发展与炎症反应密切相关,刘完素倡导的火热论对鳞癌的病机认识和治疗方法具有重要的临床指导意义。基于火热论,依据鳞癌不同阶段的病理机制及临床特点,提出癌前及鳞癌早期的病机为气机怫郁、郁热内生,术后病机为气虚不固、阴火内伏,治疗期病机为邪聚毒盛、热毒燔炎,晚期病机为阴虚毒热、痰瘀闭腑。并针对不同阶段的病机特点提出分阶段防治策略,早期疏调气机以透郁热,术后益气升阳以散伏火,治疗期清热解毒以破毒窠,晚期滋阴通腑以清虚热。It is believed that the occurrence and development of squamous cell carcinoma(SCC)is closely associated with inflammatory responses.The theory of fire and heat,advocated by LIU Wansu,provides significant clinical guidance for understanding the pathogenesis and treatment of SCC.Based on this theory,the pathological mechanisms and clinical characteristics of SCC at different stages were analyzed.In the precancerous and early stages,the primary pathogenesis is qi stagnation leading to internal generation of constrained heat;in post-surgery,the condition shifts to qi deficiency with latent yin fire;during the treatment phase,the pathogenesis involves accumulation of pathogenic factors,excess toxins,and severe heat toxicity;in the late stage,the main pathology is yin deficiency with toxic heat,and phlegm-stasis obstruction of the internal organs.Corresponding stage-based treatment strategies are proposed.In the early stage,regulating qi movement to dissipate constrained heat;for post-surgery,tonifying qi and raising yang to dispel latent fire;during treatment stage,clearing heat and detoxifying to eliminate cancerous toxins;and in the late stage,nourishing yin and unblocking the bowels to clear deficiency heat.

关 键 词：鳞状细胞癌 火热论 刘完素 分期论治 

分 类 号：R73[医药卫生—肿瘤]