肠外氨基酸营养支持联合肺功能康复训练在非小细胞肺癌术后化疗患者康复中的效果分析  

Analysis of the Effect of Parenteral Amino Acid Nutrition Support Combined with Pulmonary Function Rehabilitation Rraining in Postoperative Chemotherapy Patients with Non-Small Cell Lung Cancer

作　　者：田瑞玲 黄娜 TIAN Ruiling;HUANG Na(Department of Oncology and Hematology,Yanzhou District People’s Hospital,Jining 272000,China;Department of Respiratory and Critical Care Medicine,Yanzhou District People’s Hospital,Jining 272000,China)

机构地区：[1]山东省济宁市兖州区人民医院肿瘤血液科,山东济宁272000 [2]山东省济宁市兖州区人民医院呼吸与危重症医学科,山东济宁272000

出　　处：《中国伤残医学》2025年第7期64-67,71,共5页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:分析肠外氨基酸营养支持配合肺功能康复训练在非小细胞肺癌(NSCLC)术后化疗患者康复中的应用效果。方法:选择2021年9月—2023年9月济宁市兖州区人民医院收治的60例NSCLC术后化疗患者为研究对象,按随机数字表法将其分为对照组和研究组,各30例。对照组采取肠外氨基酸支持治疗,研究组在对照组基础上采取肺功能康复训练治疗。两组均在化疗开始后持续治疗4周。比较两组营养状况、肺功能、运动耐力、生活质量。结果:治疗后,研究组营养整体营养评估量表评分低于对照组,清蛋白和总蛋白水平高于对照组,差异均有统计学意义(P<0.05)。治疗后,研究组第1秒呼出的气体容积、用力肺活量、最大通气量及第1秒呼出的气体容积/用力肺活量均大于对照组,差异均有统计学意义(P<0.05)。治疗后,研究组6min步行试验距离长于对照组,差异有统计学意义(P<0.05)。治疗后,研究组世界卫生组织生存质量简表中各个维度评分均高于对照组,差异均有统计学意义(P<0.05)。结论:在NSCLC术后化疗患者中采取肠外氨基酸营养支持配合肺功能康复训练治疗,可改善其营养状况,促进肺功能改善,提高运动耐力,提升生活质量。Objective:To analyze the effect of parenteral amino acid nutrition support combined with pulmonary function rehabilitation training in postoperative chemotherapy patients with non-small cell lung cancer(NSCLC).Methods:A total of 60 postoperative chemotherapy patients with NSCLC admitted in Yanzhou District People’s Hospital from September 2021 to September 2023 were selected as the study objects,and divided into a control group and a study group by random number table method,with 30 cases in each group.The control group were adopted parenteral amino acid support treatment,and the study group were adopted pulmonary function rehabilitation training treatment on the basis of the control group.Both groups received continuous treatment for 4 weeks after the start of chemotherapy.The nutritional status,lung function,exercise endurance,and quality of life were compared between two groups.Results:After treatment,the Patient-Generated Subjective Global Assessment score of the study group was lower than that of the control group,the levels of clear protein and total protein of the study group were higher than those of the control group,with statistical significance(P<0.05).After treatment,the forced expiratory volume in the first second,forced vital capacity,maximum ventilation volume and forced expiratory volume in the first second/forced vital capacity were higher than those of the control group,with statistical significance(P<0.05).After treatment,the 6-min walking distance was longer than that of the control group,with statistical significance(P<0.05).After treatment,all dimensions of the scores of World Health Organization Quality of Life-BREF Scale of the study group were higher than those of the control group,with statistical significance(P<0.05).Conclusion:Parenteral amino acid nutrition support combined with pulmonary function rehabilitation training in postoperative chemotherapy patients with NSCLC can improve nutritional status,improve lung function and improve exercise endurance.

关 键 词：非小细胞肺癌 肠外氨基酸营养支持 肺功能康复训练 营养状况 运动耐力 

分 类 号：R734.2[医药卫生—肿瘤]