超声SMI技术对半夏白术天麻汤治疗痰湿壅盛型高血压颈动脉硬化斑块稳定性的评估价值  

Value of Ultrasound SMI Technique in Evaluating Stability of Carotid Atherosclerotic Plaque in Treatment of Phlegm-dampness Hypertension with Banxia Baizhu Tianma Decoction

作　　者：孙小明 翟江[1] 杨庆华[1] 孙广阳 SUN Xiao-ming;ZHAI Jiang;YANG Qing-hua;SUN Guang-yang(Department of Functional Medicine,The Second Affiliated Hospital of Hebei North University,Zhangjiakou,Hebei 075100,China;Department of Traditional Chinese Medicine,Zhangjiakou First Hospital,Zhangjiakou,Hebei 075000,China)

机构地区：[1]河北北方学院附属第二医院功能科,河北张家口075100 [2]张家口市第一医院中医科,河北张家口075000

出　　处：《河北北方学院学报(自然科学版)》2025年第8期13-16,共4页Journal of Hebei North University:Natural Science Edition

基　　金：张家口市科技计划自筹经费项目(No.2421026D)。

摘　　要：目的探讨超声超微血流显像(SMI)技术对半夏白术天麻汤治疗痰湿壅盛型高血压患者颈动脉硬化斑块稳定性的评估价值。方法采用前瞻性随机对照设计,447例痰湿壅盛型高血压患者经倾向性评分匹配(PSM)后,选取116例分为对照组(常规药物)与观察组(常规药物+半夏白术天麻汤)各58例。观察治疗前及治疗6个月后的斑块参数(IMT、Crouse积分、SMI分级、RADS评分)。结果治疗6个月后,观察组SMI 2级患者少于对照组(P<0.01),0级患者多于对照组(P<0.01);斑块不稳定发生率低于对照组(P<0.01)。2组患者颈总动脉、颈总动脉球部IMT及Crouse斑块积分、RADS评分均降低(P<0.05),观察组改善优于对照组(P<0.05)。结论应用超声SMI技术可精准评估患者颈动脉硬化斑块稳定性状态,为临床治疗效果的判定提供证据基础,值得临床参考应用。Objective To investigate the value of ultrasound superb microvascular imaging(SMI)in evaluating the stability of carotid atherosclerotic plaques in patients with hypertension of phlegm-dampness type treated with Banxia Baizhu Tianma decoction.Methods A prospective randomized controlled design was used.After propensity score matching(PSM),447 patients with hypertension of phlegm-dampness type were divided into control group(conventional drugs)and observation group(conventional drugs+Banxia Baizhu Tianma Decoction),58 cases in each group.Plaque parameters(IMT,Crouse score,SMI grade,RADS score)were observed before and 6 months after treatment.Results After 6 months of treatment,the number of patients with SMI grade 2 in the observation group was less than that in the control group(P<0.01),the number of patients with SMI grade 0 more than that in the control group(P<0.01),and the incidence of plaque instability lower than that in the control group(P<0.01).The IMT,Crouse plaque score and RADS score of common carotid artery and common carotid artery bulb were decreased in the two groups(P<0.05),and the improvement in the observation group was better than that in the control group(P<0.05).Conclusion The application of ultrasound SMI technology can accurately evaluate the stability of carotid atherosclerotic plaque in patients,and provide evidence basis for the determination of clinical treatment effect,which is worthy of clinical reference application.

关 键 词：高血压 痰湿壅盛型 超声 超微血流显像 半夏白术天麻汤 颈动脉硬化 RADS评分 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R445.1[医药卫生—临床医学]