Comment on "Early cancer detection by serum biomolecular fingerprinting spectroscopy with machine learning"  

作　　者：Ivan A.Bratchenko Lyudmila A.Bratchenko 

机构地区：[1]Laser and Biotechnical Systems Department,Samara National Research University,Moskovskoe shosse 34,Samara 443086,Russia

出　　处：《Light(Science & Applications)》2025年第2期564-565,共2页光(科学与应用)(英文版)

基　　金：findings of this paper were supported by the Russian Science Foundation ProjectNo.21-75-10097.

摘　　要：Dear Editor,In their recent publication,Dong et al.l demonstrated high performance of SERS-based liquid biopsy of human serum analysis for earlier cancer detection.Moreover,this study was highlighted in News&Vies section of Light Science and Applications journal by Shi et al.?.No doubt,different optical techniques nowadays are widely used for the analysis of biofluids and liquid biopsy33-10 and demonstrate high accuracy in possible clinical applications.At the same time,the paper by Dong et al.may be treated incorrectly due to the drawbacks in spectral data analysis.

关 键 词：liquid biopsy machine learning spectral data analysis surface enhanced Raman scattering human serum optical techniques early cancer detection 

分 类 号：R730.4[医药卫生—肿瘤] R730.43[医药卫生—临床医学]