探讨药学干预指导在抑郁症伴睡眠障碍患者中的应用效果  

Exploring the Application Effect of Pharmaceutical Intervention Guidance in Patients with Depression Accompanied by Sleep Disorders

作　　者：王洁 李泽辉 WANG Jie;LI Zehui(Zhaotong Health Vocational College,Zhaotong 657000,China;Zhaotong First People′s Hospital,Zhaotong 657000,China)

机构地区：[1]昭通卫生职业学院,昭通657000 [2]昭通市第一人民医院,昭通657000

出　　处：《世界睡眠医学杂志》2025年第1期211-214,共4页World Journal of Sleep Medicine

摘　　要：目的:探讨药学干预指导在抑郁症伴睡眠障碍患者中的应用效果。方法:选取2023年1月至2023年12月昭通卫生职业学院收治的抑郁症伴睡眠障碍患者42例作为研究对象,按照随机数字表法分为对照组和观察组,每组21例。对照组给予常规指导干预,观察组给予药学干预指导。采用匹兹堡睡眠质量指数(PSQI)比较2组患者睡眠质量的差异,采用抑郁自评量表(SDS)、焦虑自评量表(SAS)比较2组患者干预前后焦虑、抑郁的改善情况,采用失眠严重程度指数量表(ISI)评价2组患者干预前后失眠症状的改善效果,采用睡眠状态评分参考睡眠状况自评量表(SRSS)比较2组患者睡眠障碍的发生情况,并比较2组患者的治疗依从性。结果:治疗后,观察组PSQI评分、SDS评分、SAS评分、ISI评分、SRSS评分均显著低于对照组,观察组遵医依从性显著高于对照组,差异均有统计学意义(均P<0.05)。结论:药学干预指导能够有效改善抑郁症伴睡眠障碍患者的睡眠质量,减轻其负性心理状态,并提升患者的遵医依从性。干预作为一种辅助治疗方法,在抑郁症伴睡眠障碍患者中的应用可行且有效。Objective:To explore the application effect of pharmaceutical intervention guidance in patients with depression accompanied by sleep disorders.Methods:A total of 42 patients with depression and sleep disorders admitted to Zhaotong Health Vocational College from January 2023 to December 2023 were selected as the research subjects.They were divided into a control group and an observation group using a random number table method,with 21 patients in each group.The control group received routine guidance intervention,while the observation group received pharmaceutical intervention guidance intervention.The Pittsburgh Sleep Quality Index(PSQI)was used to compare the differences in sleep quality between two groups.The Self Rating Depression Scale(SDS)and Self Rating Anxiety Scale(SAS)were used to compare the improvement of anxiety and depression before and after intervention in the two groups of patients.The Insomnia Severity Index(ISI)was used to evaluate the improvement effect of insomnia symptoms before and after intervention.The Sleep Status Score(SRSS)was used to compare the occurrence of sleep disorders in the two groups,and the treatment compliance of the two groups was compared.Results:After treatment,the PSQI score,SDS score,SAS score,ISI score,and SRSS score in the observation group were significantly lower than those in the control group.The compliance with medical treatment in the observation group was significantly higher than that in the control group,and the differences between the two groups were statistically significant(P<0.05).Conclusion:Pharmaceutical intervention guidance can effectively improve the sleep quality of patients with depression accompanied by sleep disorders,alleviate their negative psychological state,and enhance their compliance with medical treatment.As an auxiliary treatment method,pharmaceutical intervention is feasible and effective in patients with depression and sleep disorders.

关 键 词：抑郁症 睡眠障碍 药学干预 睡眠质量 焦虑 抑郁 依从性 负性心理 

分 类 号：R749.41[医药卫生—神经病学与精神病学] R338.63[医药卫生—临床医学]