体温控制对肺癌患者术后应激反应及恢复进程的影响  

Effect of body temperature control on postoperative stress response and recovery process in patients with lung cancer

作　　者：贾波[1] 曹利华 杨晓新 赵玉苗 JIA Bo;CAO Lihua;YANG Xiaoxin;ZHAO Yumiao(Department of Respiratory Medicine,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450007,He’nan,China)

机构地区：[1]郑州大学第一附属医院呼吸内科,郑州450007

出　　处：《癌症进展》2025年第6期669-672,共4页Oncology Progress

基　　金：河南省医学科技攻关计划省部共建青年项目(SBGJ202003022)。

摘　　要：目的探讨体温控制对肺癌患者术后应激反应及恢复进程的影响。方法根据干预方法的不同将126例肺癌手术患者分为对照组(n=62,常规干预)和观察组(n=64,在常规干预的基础上于麻醉恢复室实施体温控制)。比较两组患者的体温、应激反应指标[皮质醇(Cor)、去甲肾上腺素(NE)]、术后恢复指标及并发症发生情况。结果进入麻醉恢复室10、20 min后,观察组患者体温均明显高于对照组,差异均有统计学意义(P﹤0.01)。术后1天,观察组患者Cor、NE水平均明显低于对照组,差异均有统计学意义(P﹤0.01)。观察组患者术后苏醒时间、麻醉恢复室停留时间、气管导管拔出时间均明显短于对照组,差异均有统计学意义(P﹤0.01)。观察组患者术后并发症总发生率为6.25%,低于对照组患者的20.97%,差异有统计学意义(P﹤0.05)。结论体温控制有利于维持肺癌手术患者术后体温稳定,预防低体温的发生,还可降低应激反应指标和并发症发生率,促进患者术后尽快苏醒,避免术后躁动及苏醒延迟的发生。Objective To explore the effect of body temperature control on postoperative stress response and recovery process in patients with lung cancer.Method According to different intervention methods,126 patients with lung cancer who underwent surgery were divided into control group(n=62,received routine intervention)and observation group(n=64,received body temperature control in the anesthesia recovery room on the basis of routine intervention).The body temperature,stress response indexes[cortisol(Cor),norepinephrine(NE)],postoperative recovery indexes and complications were compared between the two groups.Result After entering the anesthesia recovery room for 10 and 20 minutes,the body temperature of the observation group was significantly higher than those of the control group,and the differences were statistically significant(P<0.01).One day after surgery,the Cor and NE levels in observation group were significantly lower than those in control group,and the differences were statistically significant(P<0.01).The postoperative recovery time,stay time in the anesthesia recovery room,and endotracheal tube extraction time in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(P<0.01).The total incidence of postoperative complications in the observation group was 6.25%,lower than 20.97%in the control group,and the difference was statistically significant(P<0.05).Conclusion Body temperature control is conducive to maintaining the stable body temperature of patients with lung cancer undergoing surgery,preventing the occurrence of hypothermia,reducing the stress response indexes and the incidence of complications,promoting the rapid recovery of patients after surgery,and avoiding the occurrence of postoperative agitation and delayed recovery.

关 键 词：肺癌 体温控制 应激反应 恢复进程 

分 类 号：R734.2[医药卫生—肿瘤]