TLDG与LADG应用于老年胃癌患者的效果比较  

Comparison of Effects of TLDG and LADG in Elderly Patients with Gastric Cancer

作　　者：谢立飞 蒋恺[1] XIE Lifei;JIANG Kai(Affiliated Hospital of Jiangnan University,Wuxi 214062,China)

机构地区：[1]江南大学附属医院,江苏无锡214062

出　　处：《中外医学研究》2025年第9期45-48,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究比较全腔镜远端胃癌根治术(TLDG)与腹腔镜辅助胃癌根治术(LADG)应用于老年胃癌患者中的效果。方法:选取2022年1月-2024年1月江南大学附属医院收治的60例胃癌患者开展研究。以电脑编号单双数法将其随机分为全腔镜组(n=30)与辅助组(n=30)。全腔镜组选用TLDG治疗,辅助组则选用LADG治疗。比较两组治疗效果(评估指标涵盖手术指标,炎症因子,免疫指标,并发症)。结果:全腔镜组术中失血量少于辅助组,术后排气时间、进食时间与住院天数均短于辅助组,差异有统计学意义(P<0.05);术后3 d两组各项血清炎症因子水平均高于术前,但全腔镜组低于辅助组,差异有统计学意义(P<0.05);术后3 d两组各项免疫功能指标水平均低于术前,但全腔镜组高于辅助组,差异有统计学意义(P<0.05)。结论:相较于LADG,TLDG应用于老年胃癌患者中的效果更理想,可促进患者早日康复,减轻手术产生的炎症反应与免疫功能下降程度,且不会增加并发症发生风险。Objective:To study the effect of totally laparoscopic distal gastrectomy(TLDG)and laparoscopic assisted distal gastrectomy(TLDG)in elderly patients with gastric cancer.Method:A total of 60 patients with gastric cancer admitted to the Affiliated Hospital of Jiangnan University from January 2022 to January 2024 were selected for this study.They were randomly divided into full cavity mirror group(n=30)and auxiliary group(n=30)by computer numbering method.TLDG was used in the endoscopic group and LADG was used in the auxiliary group.The results of the two groups were compared(evaluation indicators included surgical indicators,inflammatory factors,immune indicators,complications).Result:The intraoperative blood loss in the total endoscopy group was less than that in the auxiliary group,and the postoperative exhaust time,feeding time and hospitalization days were shorter than those in the auxiliary group,with statistical significance(P<0.05).The levels of serum inflammatory factors in 2 groups were higher than before 3 days after surgery,but the total endoscopy group was lower than the auxiliary group,and the difference was statistically significant(P<0.05).The levels of all immune function indexes in the two groups were lower than those before surgery,but the total endoscopy group was higher than the auxiliary group,with statistical significance(P<0.05).Conclusion:Compared with LADG,the application of TLDG in elderly patients with gastric cancer has a better effect,which can promote the early recovery of patients,reduce the degree of inflammation and immune function decline caused by surgery,and will not increase the risk of complications.

关 键 词：胃癌 老年 全腔镜远端胃癌根治术 腹腔镜辅助胃癌根治术 炎症因子 免疫功能 

分 类 号：R735.2[医药卫生—肿瘤]