Penumbra系统联合Reco支架介入取栓术对急性脑梗死患者血管再通率和血流动力学的影响  

The Impact of Penumbra System Combined with Reco Stent Interventional Thrombectomy on the Recanalization Rate and Hemodynamics in Patients with Acute Ischemic Stroke

作　　者：蒋德峰 陈艳[1] 王诗慧 JIANG Defeng;CHEN Yan;WANG Shihui(Siyang Hospital of Traditional Chinese Medicine affiliated to Yangzhou University Medical College,Siyang 223700,China)

机构地区：[1]扬州大学医学院附属泗阳中医院,江苏泗阳223700

出　　处：《中外医学研究》2025年第9期71-74,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:评估Penumbra系统联合Reco支架介入取栓术对急性脑梗死(AIS)患者血管再通率和血流动力学的影响。方法:选取2022年2月-2024年2月扬州大学医学院附属泗阳县中医院收治的96例急性脑梗死患者作为研究对象,按随机数表法分为研究组(n=48)和对照组(n=48)。研究组给予溶栓+Penumbra系统联合Reco支架介入取栓术治疗,对照组给予溶栓治疗。采用统计学方法评估的血管再通率、血流动力学参数[全血高切黏度(HSV)、全血低切黏度(LSV)和血浆黏度(PV)]、神经功能采用[美国国立卫生院脑卒中量表(NIHSS)]、血管内皮功能[血清一氧化氮(NO)、内皮素(ET)],并记录并发症的发生情况。结果:治疗后,研究组HSV、LSV、PV低于对照组,差异有统计学意义(P<0.05);NIHSS评分、ET水平低于对照组,差异有统计学意义(P<0.05);NO水平高于对照组,差异有统计学意义(P<0.05)。治疗后,两组并发症发生率比较,差异无统计学意义(P>0.05)。结论:Penumbra系统联合Reco支架介入取栓术能显著提高急性脑梗死患者的血管再通率和改善血流动力学参数。Objective:This study aims to evaluate the effects of the Penumbra system combined with Reco stent interventional thrombectomy on the recanalization rate and hemodynamics in patients with acute ischemic stroke(AIS).Method:Ninety-six patients with acute cerebral infarction admitted to Siyang Hospital of Traditional Chinese Medicine,Affiliated to Yangzhou University Medical College from February 2022 to February 2024 were selected as the study objects,and were divided into study group(n=48)and control group(n=48)according to random number table method.The study group received thrombolysis plus Penumbra system combined with Reco stent,and the control group received thrombolysis.Vascular revascularization rate,hemodynamic parameters[Hematocrit high shear viscosity(HSV),low shear viscosity(LSV),and plasma viscosity(PV)],neurological function[using the National Institutes of Health Stroke Scale(NIHSS)],vascular endothelial function[serum nitric oxide(NO),endothelin(ET)]as assessed by statistical methods,Complications were recorded.Result:After treatment,HSV,LSV and PV in the study group were lower than those in the control group,and the difference was statistically significant(P<0.05).NIHSS score and ET level were lower than control group,the difference was statistically significant(P<0.05).The level of NO was higher than that of control group,and the difference was statistically significant(P<0.05).After treatment,there was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusion:Penumbra system combined with Reco stent can significantly improve the vascular revascularization rate and hemodynamic parameters in patients with acute cerebral infarction.

关 键 词：Penumbra系统 Reco支架 介入取栓术 急性脑梗死 血流动力学 

分 类 号：R743.3[医药卫生—神经病学与精神病学]