低频脉冲电脉刺激联合Beckman口肌训练治疗帕金森病伴流涎患者的疗效观察  

Combining low-frequency pulsed electrical stimulation with Beckman oral muscle training can better relieve droolingin Parkinson'sdisease

作　　者：王丽 石小雪 魏晓艳 郑银燕 张雪妨 冯凯伦 何欢 李学 马建军 Wang Li;Shi Xiaoxue;Wei Xiaoyan;Zheng Yinyan;Zhang Xuefang;Feng Kailun;He Huan;Li Xue;Ma Jianjun(Department of Neurology,Henan Provincial People's Hospital,People's Hospital of Zhengzhou University,People's Hospital of Henan University,Zhengzhou 450003,China)

机构地区：[1]河南省人民医院神经内科,郑州大学人民医院,河南大学人民医院,郑州450003

出　　处：《中华物理医学与康复杂志》2025年第3期232-236,共5页Chinese Journal of Physical Medicine and Rehabilitation

基　　金：河南省卫生健康委员会项目(SBGJ202102035,LHGJ20230054);河南省科技研发计划联合基金项目(225200810068)。

摘　　要：目的观察低频脉冲电刺激联合Beckman口肌训练治疗帕金森病(PD)伴流涎患者的疗效。方法采用随机数字表法将120例PD伴流涎患者分为口肌训练组、电刺激组及观察组,每组40例。3组患者均给予常规药物治疗,在此基础上口肌训练组、电刺激组分别辅以Beckman口肌训练或低频脉冲电刺激治疗,观察组则辅以低频脉冲电刺激及Beckman口肌训练联合干预。于治疗前、治疗4周后分别采用流涎评定量表(DRS)、PD流涎临床量表(SCS-PD)、反复唾液吞咽测试(RSST)、口部运动功能评级、唾液称重测试和PD生活质量问卷(PDQ-39)对3组患者的流涎严重程度、反复空吞咽次数、口腔运动功能、唾液聚积情况及生活质量等进行评定。结果治疗后观察组患者DRS、SCS-PD、PDQ-39评分[分别为(5.2±1.55)分、(12.45±2.53)分和(50.23±15.30)分]及唾液称重[(0.92±0.32)g]均较治疗前及同期电刺激组、口肌训练组明显减少(P<0.05),RSST[(3.28±0.85)次]、口腔运动功能评分[(79.08±8.37)分]均较治疗前及同期电刺激组、口肌训练组显著增加(P<0.05)。结论低频脉冲电刺激联合Beckman口肌训练可进一步改善PD伴流涎患者的口腔运动功能、吞咽功能及生活质量,减轻流涎症状,其疗效优于单一低频脉冲电刺激或Beckman口肌训练,该联合疗法值得临床推广、应用。Objective To observe the therapeutic effect of combining low-frequency pulsed electrical stimulation with Beckman oral muscle exercise training in relieving drooling among persons with Parkinson′s disease(PD).Methods A random number table was used to divide 120 PD patients with drooling into a mouth muscle training group,an electrical stimulation group,and an observation group,with 40 patients in each group.In addition to routine medication,the oral muscle training group was given Beckman oral muscle exercise training,the electrical stimulation group underwent low-frequency pulsed electrical stimulation treatment,while the observation group was provided with both.Before and after 4 weeks of treatment,the severity of salivation,the frequency of repeated empty swallowing,oral motor function,saliva secretion,and life quality of the three groups were evaluated using the Saliva Rating Scale(DRS),the Repeated Saliva Swallowing Test(RSST),oral motor function grading,the Parkinson′s Disease Saliva Clinical Scale(SCS-PD),saliva weighing,and the PD Quality of Life Scale(PDQ-39).Results After the treatment the average DRS,SCS-PD,saliva weighing and PDQ-39 results of the observation group were significantly better than those before treatment and better than the other 2 groups′averages.That group′s average RSST and oral motor function scores had increased significantly compared to before treatment,and compared with the other 2 groups′averages at the same time point.Conclusions Combining low-frequency pulsed electrical stimulation with Beckman oral muscle exercise can improve oral motor function,swallowing,and the life quality of PD patients who drool.It is more effective than electrical stimulation or oral muscle exercise training alone.Such combination therapy is worthy of clinical promotion and application.

关 键 词：低频脉冲电刺激 口肌训练 帕金森病 流涎 非运动症状 

分 类 号：R742.5[医药卫生—神经病学与精神病学]