固相萃取光度法测定药物中铁的实验教学探索  

Experimental Teaching Exploration on Determination of Iron in Herbs by Solid-phase Extraction Spectrophotometry

作　　者：金苹 蒲沁琳 刘良红 李嘉 吴方评 JIN Ping;PU Qinlin;LIU Lianghong;LI Jia;WU Fangping(School of Pharmaceutical Sciences,Hunan University of Medicine,Hunan Huaihua 418000,China)

机构地区：[1]湖南医药学院药学院,湖南怀化418000

出　　处：《广州化工》2025年第6期212-215,共4页GuangZhou Chemical Industry

基　　金：湖南省教育厅教学改革项目(No:2019518);湖南省一流课程支撑项目(No:2021841);湖南医药学院教改项目(No:2022JG31)。

摘　　要：随着固相萃取样品前处理技术的产生与完善,其在科学研究、环境检测、临床药物监测、产品质量监控等领域的应用日趋广泛。为了使学生更好地掌握这一技术,我们将其应用于高校药学及相关专业的实验教学中,构建了固相萃取富集分光光度法来测定药物样品中的痕量铁的方法。此方法具有速度快、消耗少、富集倍数高、不易乳化等优势,不仅丰富了实验教学内容,还有助于激发学生的学习和科研兴趣,提高学生运用所学知识解决生活和生产中实际问题的实践能力,有益于应用型和创新型药学人才的培养,符合高校人才培养的目的。With the development and refinement of solid-phase extraction(SPE)sample pretreatment technology,its applications in scientific research,environmental monitoring,clinical pharmacotherapy,product quality control,and other fields have become increasingly widespread.To facilitate students´mastery of this technique,SPE into experimental teaching for Pharmacy and related university majors was integrated,developing a method for determining trace iron in drug samples using SPE-enriched spectrophotometry.This method offered advantages such as rapid analysis,low organic solvent consumption,high enrichment efficiency and minimal emulsification.It not only enriched experimental teaching content,but also fostered students´interest in learning and research,enhanced their practical ability to apply theoretical knowledge to solve real-world problems in life and industry,and promoted the cultivation of applied and innovative pharmaceutical talents,aligning with modern university education objectives.

关 键 词：固相萃取 高铁试剂 分光光度法 实验教学 

分 类 号：G642[文化科学—高等教育学]