新生儿早期基本保健核心干预措施的卫生经济学评价  

Health economics evaluation of core interventions in early essential newborn care

作　　者：胡焕青 徐韬 Hu Huanqing;Xu Tao(National Center for Women and Children's Health,NHC,PRC,Beijing 100089,China)

机构地区：[1]国家卫生健康委妇幼健康中心,北京100089

出　　处：《中华围产医学杂志》2025年第3期219-225,共7页Chinese Journal of Perinatal Medicine

摘　　要：目的了解新生儿早期基本保健(early essential newborn care,EENC)核心干预措施的卫生经济学评价研究现状。方法以“新生儿早期保健”“出生窒息复苏”“袋鼠式护理”“新生儿维生素K”“卫生经济学”“成本”或“效益”或“效果”等关键词的排列组合检索中国知网、万方数据、中华医学期刊全文数据库和维普中文期刊数据库等中文数据库。以“economic evaluation”“assessing”“cost”“cost-effective”“effective”“effect”“kangaroo mother care or KMC”“resuscitation of neonatal asphyxia/help baby breathe/neonatal asphyxia”“injection of vitamin K_(1)/intramuscular vitamin K_(1)neonatal/newborns”等EENC核心干预措施为关键词检索PubMed、EmBase、Springer、谷歌学术和Web of Science等数据库。对检索得到的文献进行筛选。按照卫生经济研究质量评价工具(Quality of Health Economic Studies,QHES)和对纳入的文献进行质量评价。通过阅读文献,分析纳入文献的研究类型、研究对象、主要指标及研究结果,并进行归纳总结。结果共16篇文献最终纳入本研究,其中KMC相关9篇(其中2篇无真实世界数据,仅为统计模型研究),新生儿复苏相关4篇(均无真实世界数据),注射维生素K_(1)相关3篇(其中1篇无真实世界数据)。未检索到关于EENC其他核心干预措施的文献。8篇文献为基于既往卫生系统或医院数据的分析,4篇文献为随机对照试验,2篇为基于方便抽样的回顾性分析,2篇为项目实施前后的效果对比。仅2篇研究采用了2018年以后的数据。对纳入的16篇文献应用QHES工具进行评价,其中只有3篇文献质量较好。干预措施的卫生经济学评价方面,纳入的研究认为,实施KMC更有效且成本更低,全部复苏和选择性复苏是具有成本效益的策略,新生儿肌内注射维生素K_(1)是具有成本效益的干预措施。结论目前关于EENC干预措施的卫生经济学评价研究�ObjectiveTo investigate the status of health economics evaluation studies on the core interventions in early essential newborn care(EENC).MethodsRelevant articles were retrieved from Chinese databases including CNKI,Wanfang Data,Yiigle,and VIP Chinese Journals using keywords in Chinese,including"early neonatal care,""resuscitation of birth asphyxia,""kangaroo mother care(KMC)""neonatal vitamin K,""health economics,"and"cost,""benefit,"or"effect"and from databases such as PubMed,Embase,Springer,Google Scholar,and Web of Science using keywords such as"economic evaluation,""assessing,""cost,""cost-effective,""effective,""effect,""kangaroo mother care or KMC,""resuscitation of neonatal asphyxia/help baby breathe/neonatal asphyxia,""injection of vitamin K_(1)/intramuscular vitamin K_(1)neonatal/newborns"and other core interventions in EENC.The retrieved literature was screened.The quality of the included articles was evaluated according to the Quality of Health Economic Studies(QHES)instrument.The research objects,types,main indicators,and results were summarized.ResultsA total of 16 articles were finally included in this study,including nine related to KMC(of which two had no real-world data and were only statistical model studies),four related to neonatal resuscitation(all without real-world data),and three related to intramuscular injection of vitamin K_(1)(of which one had no real-world data).No articles on other core interventions in EENC were retrieved.There were eight articles based on the analysis of previous health system or hospital data,four using a randomized controlled trial,two retrospective studies based on convenience sampling,and two comparing the effects before and after a project.Only two studies used the data from 2018 onwards.The 16 included articles were evaluated according to QHES and only three were rated as excellent.Regarding health economics evaluation of intervention measures,the included studies believed implementing KMC was more effective and less costly.Full resuscitation,selective resus

关 键 词：卫生经济学评价 新生儿早期基本保健 袋鼠式护理 新生儿复苏 

分 类 号：R722.1[医药卫生—儿科]