口腔微生物在牙周健康中的作用研究进展  

Role of oral microbiota in periodontal health:research progress

作　　者：钱泉 刘银辉[2] QIAN Quan;LIU Yinhui(Huayang Stomatological Hospital,Cixi,Zhejiang 315300,China;不详)

机构地区：[1]华阳口腔医院,浙江慈溪315300 [2]大连医科大学微生态学教研室

出　　处：《中国微生态学杂志》2025年第2期228-232,239,共6页Chinese Journal of Microecology

摘　　要：饮食或唾液等的变化会引起牙菌斑沉积,当沉积到一定程度后可能导致牙龈炎甚至发展为牙周炎。这两种疾病是最常见的牙周疾病,一般采用根面平整、龈上清洁和深袋清创等机械疗法治疗,再辅以药物抗菌治疗。随着人们对口腔微生物群重要性认识的加深,通过添加口腔益生菌和移植口腔微生物组来治疗牙周疾病的方法受到更多的青睐。上述方法是通过添加的益生菌来调节口腔微生物群的失调,益生菌与病原菌竞争营养物质和黏附表面,从而抑制病原菌的生长。由于牙周疾病的高发及其对人体健康的不利影响,有必要开发新的预防措施和有效的牙周疾病治疗方法。Changes in diet or saliva will cause plaque accumulation,which may lead to gingivitis or even periodontitis after accumulation to a certain extent.These two diseases are the most common periodontal diseases,which are generally treated with mechanical therapy such as root surface flattening,supragingival cleaning and deep pocket debridement,and then supplemented by antimicrobial treatment with drugs.With the deepening of people's understanding on the importance of oral microbiota,the addition of oral probiotics and transplantation of oral microbiota in the treatment of periodontal diseases began to receive more attention.This approach is to adjust the imbalance of oral flora by adding probiotics that compete with pathogenic bacteria for nutrients and adhesion to surfaces,thus inhibiting the growth of pathogenic bacteria.Due to the high incidence of periodontal diseases and their adverse effects on human health,it is necessary to develop new preventive measures and effective therapies for periodontal diseases.

关 键 词：牙龈炎 口腔微生物组 肠道微生物组 牙周病原体 牙周炎 

分 类 号：R78[医药卫生—口腔医学]