种植单冠修复后种植体周健康的相关分析  

Correlation analysis of peri-implant health after single-tooth dental implant

作　　者：林芳汝 唐志辉[2] LIN Fangru;TANG Zhihui(Department of Periodontology,Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical Devices&Beijing Key Laboratory of Digital Stomatology&NHC Research Center of Engineering and Technology for Computerized Dentistry&NMPA Key Laboratory for Dental Materials,Beijing 100081,China;Second Clinical Division,Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical Devices&Beijing Key Laboratory of Digital Stomatology&NHC Research Center of Engineering and Technology for Computerized Dentistry&NMPA Key Laboratory for Dental Materials,Beijing 100081,China)

机构地区：[1]北京大学口腔医学院·口腔医院牙周科,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔生物材料和数字诊疗装备国家工程研究中心,口腔数字医学北京市重点实验室,国家卫生健康委员会口腔医学计算机应用工程技术研究中心,国家药品监督管理局口腔生物材料重点实验室,北京100081 [2]北京大学口腔医学院·口腔医院第二门诊部,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔生物材料和数字诊疗装备国家工程研究中心,口腔数字医学北京市重点实验室,国家卫生健康委员会口腔医学计算机应用工程技术研究中心,国家药品监督管理局口腔生物材料重点实验室,北京100081

出　　处：《北京大学学报(医学版)》2025年第2期347-353,共7页Journal of Peking University:Health Sciences

摘　　要：目的:追踪观察第一磨牙种植单冠修复后种植体的健康情况,评估影响种植体周健康的相关因素。方法:选择2008年1月至2020年12月就诊于北京大学口腔医院第二门诊部,行第一磨牙种植单冠修复的82位患者作为研究对象,共278个负重1年以上的种植体,记录种植体周的探诊深度(peri-implant probing depth,PPD)、改良出血指数(modified sulcus bleeding index,mSBI)、改良菌斑指数(modified plaque index,mPLI)、龈乳头指数(papilla index,PI),进行临床资料回顾及X线片的测量分析,X线片分析内容包括修复体穿龈角度(restoration emergence angle,REA)、种植牙临床冠根比(clinical crown-implant ratio,cC/I)、种植牙与邻牙牙根之间的水平距离(horizontal tooth-implant distance,HTID)、邻间隙高度(contact point level,CPL)、邻间隙面积(embrasure surface area,ESA)等。结果:患者平均手术年龄为(40.2±9.5)岁(19~84岁),男性33例,女性49例,随访时间为(4.9±3.3)年(1~10年)。根据2018年的诊断标准,种植体周炎患病率在种植体水平为14.03%,患者水平为21.95%;种植体周健康率在种植体水平为19.06%,患者水平为18.29%;种植体周黏膜炎患病率在种植体水平为66.91%,患者水平为59.75%。种植体周健康组与种植体周炎组在负重1年时(基线)PPD、远中HTID、近中/远中CPL、cC/I,两组间差异具有统计学意义(P<0.05),而mSBI、mPLI、PI、近中HTID、近中/远中REA、近中/远中ESA组间差异无统计学意义(P>0.05)。在随访与基线之间的差值中,PPD、近中/远中HTID、近中/远中CPL、近中/远中ESA在两组间差异具有统计学意义(P<0.05)。广义估计方程分析显示,PPD、近中/远中HTID、近中CPL以及近中ESA随访与基线的差值,与发生种植体周炎风险存在显著正相关。结论:基于本研究结果,种植体周健康率仍不理想,种植体周探诊深度以及种植体与邻牙的关系(如HTID、CPL、ESA)与种植体周健康相关。Objective:To observe the long-term health condition of the single-tooth dental implant at the first molar site,and to evaluate the related factors affecting the peri-implant health.Methods:In this study,82 patients who were treated in the Second Clinical Division,Peking University School and Hos-pital of Stomatology from January 2008 to December 2020 were enrolled.Peri-implant tissue conditions were assessed by clinical and radiographic examination.The peri-implant probing depth(PPD),modified sulcus bleeding index(mSBI),modified plaque index(mPLI)and papilla index(PI)were recorded for 278 implants.The X-ray analysis included the restoration emergence angle(REA),the clinical crown-implant ratio(cC/I),the horizontal tooth-implant distance(HTID),the contact point level(CPL)and the embrasure surface area(ESA),etc.Kruskal-Wallis rank sum test and generalized estimation equation were used for statistical analysis.Results:The average age of the patients was(40.2±9.5)years(19 to 84 years),with 33 males and 49 females.The follow-up time was(4.9±3.3)years(1 to 10 years).According to the diagnostic criteria in 2018,the prevalence of peri-implantitis in this study was 14.03% on the implant level and 21.95% on the patient level.The peri-implant health rate was 19.06% on the implant level and 18.29% on the patient level.The prevalence of peri-implant mucositis was 66.91% on the implant level and 59.75% on the patient level.At the baseline,there were statistically significant differences between the peri-implant health group and peri-implantitis group in PPD,distal HTID and mesial/distal CPL,cC/I(P<0.05),while there was no statistically significant difference in mSBI,mPLI,PI,mesial HTID,mesial/distal REA and mesial/distal ESA between the two groups.Among the differences between follow-up and baseline,there were statistically significant dif-ferences between the two groups in PPD,mesial/distal HTID,mesial/distal CPL and mesial/distal ESA(P<0.05).Generalized estimation equation showed that PPD,mesial/distal HTID,mesial CPL,and

关 键 词：种植体周炎 口腔种植单冠修复 患病率 种植体周健康 邻间隙面积 

分 类 号：R783.6[医药卫生—口腔医学]