中枢神经系统非典型畸胎样/横纹肌样瘤的研究进展  

Research progress of atypical teratoid/rhabdoid tumor of the central nervous system

作　　者：韩蕙如 琚璐 郑诗祺 任国涛 王立峰[1] Han Huiru;Ju Lu;Zheng Shiqi;Ren Guotao;Wang Lifeng(Department of Pathology,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200092,China)

机构地区：[1]上海交通大学医学院附属新华医院病理科,上海200092

出　　处：《临床与实验病理学杂志》2025年第3期380-384,共5页Chinese Journal of Clinical and Experimental Pathology

基　　金：国家卫生健康委能力建设和继续教育中心(BLC2023JJSJ008)。

摘　　要：非典型畸胎样/横纹肌样瘤(atypical teratoid/rhabdoid tumor,AT/RT)是一种罕见的、高度恶性的中枢神经系统肿瘤,预后差,常发生于3岁以下的儿童。该文将从AT/RT的临床病理特征、分子亚型、发病机制、治疗、预后、相关的临床试验以及存在的问题等进行综述,以加深对AT/RT的认识。Atypical teratoid/rhabdoid tumor(AT/RT)is a rare,highly malignant central nervous system tumor with a poor prognosis and often occurs in children under 3 years of age.In this article,the clinicopathological features,molecular subtypes,pathogenesis,treatment,prognosis,relevant clinical trials,and existing problems of AT/RT will be reviewed to deepen the understanding of AT/RT.

关 键 词：非典型畸胎样/横纹肌样瘤 分子亚型 发病机制 文献综述 

分 类 号：R739.41[医药卫生—肿瘤]