唾液预测儿童龋病的研究进展  

RESEARCH PROGRESS IN SALIVA PREDICTION OF CHILDHOOD CARIES

作　　者：闫红岩 咏梅[2] YAN Hongyan;Yongmei(Inner Mongolia Medical University,Hohhot 010059,China;Department of Dentistry,The Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010050,China)

机构地区：[1]内蒙古医科大学,内蒙古呼和浩特010059 [2]内蒙古医科大学附属医院口腔科,内蒙古呼和浩特010050

出　　处：《内蒙古医科大学学报》2025年第1期93-96,103,共5页Journal of Inner Mongolia Medical University

基　　金：内蒙古自治区卫生健康科技计划项目(202202201)。

摘　　要：龋病是危害儿童健康的常见病和多发病。儿童龋病发病早、进展快,不仅影响咀嚼功能,且对恒牙发育和萌出甚至对儿童身心健康都有一定程度的危害。近年来,随着龋病的危害被广泛普及以及人们防龋意识提高,诊断早期龋的研究也更加深入。龋活跃性检测表示个体或群体可能患龋的敏感程度,依据所测结果,可以区分出龋病高危人群,对于预测患龋风险、筛选易感人群、进行有针对性的靶向干预具有重要意义。唾液由于其易用性、现场应用、非侵入性可以提高儿童接受度和配合度,越来越多地被用作诊断和监测各种疾病进展的初筛方法。本文就近年来国内外对唾液预测儿童龋病的研究进展作一综述。Caries is a common and frequently occurring disease that endangers the health of children and adolescents.Caries progress rapidly and do harm to the development and eruption of permanent teeth,as well as physical and mental health.In recent years,with the widespread spread of the hazards of caries and the improvement of caries prevention awareness,research on the diagnosis of early caries has become more in-depth.Caries activity test indicates an individual’s or group's sensitivity to develop dental caries,so that we can understand how high their level of dental caries activity is.Based on this,identify people who have a higher risk of tcaries,which is very important for predicting the occurrence of dental caries,screening susceptible groups,and carrying out targeted interventions.Salivary biomarkers are increasingly being used as a primary screening method for diagnosing and monitoring the progression of various diseases due to their ease of use,on-site application,and non-invasive ability to improve children's acceptance and compatibility.This article reviews the research progress on saliva prediction of childhood caries in recent years both domestically and internationally.

关 键 词：儿童龋病 唾液 预测 龋活跃性 

分 类 号：R788.1[医药卫生—口腔医学]