神经介入取栓联合替罗非班溶栓治疗急性脑梗死的效果  

Effect of Neurointerventional Thrombectomy Combined with Tirofiban Thrombolysis in the Treatment of Acute Cerebral Infarction

作　　者：苏宁 王程琳 汪宁[1] 孙军[1] SU Ning;WANG Chenglin;WANG Ning;SUN Jun(Department of Neurology,Nanyang Central Hospital,Nanyang 473000,Henan,China)

机构地区：[1]河南省南阳市中心医院神经内科,河南南阳473000

出　　处：《中国药物滥用防治杂志》2025年第2期305-307,共3页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：河南省科学技术厅科技发展计划项目(编号:192102310349)。

摘　　要：目的:分析神经介入取栓联合替罗非班溶栓对急性脑梗死的临床疗效。方法:选择本院2023年3月—2024年3月160例急性脑梗死患者为研究对象,按盲抽法分组,对照组(n=80)实施神经介入取栓,研究组(n=80)联用神经介入取栓+替罗非班溶栓,比较两组治疗后血管再通、脑血流动力学及神经功能状况。结果:治疗后,研究组血管再通率为95.00%,高于对照组的77.50%(P<0.05);研究组穿刺成功-再通时间、RI、PI、NIHSS分低于对照组,MV高于对照组(P<0.05)。结论:联用神经介入取栓、替罗非班溶栓能提高急性脑梗死的血管再通率,改善脑神经功能,效果显著。Objective:To analyze the clinical efficacy of neurointerventional thrombectomy combined with tirofiban thrombolysis in acute cerebral infarction.Methods:A total of 160 patients with acute cerebral infarction in our hospital from March 2023 to March 2024 were selected as the research objects and divided into two groups according to the blind sampling method.The control group(n=80)was treated with neurointerventional thrombectomy,and the study group(n=80)was treated with neurointerventional thrombectomy+tirofiban thrombolysis.The vascular recanalization,cerebral hemodynamics and neurological function were compared between the two groups after treatment.Results:After treatment,the vascular recanalization rate of the study group was 95.00%,which was higher than 77.50%of the control group(P<0.05).The puncture success-recanalization time,RI,PI and NIHSS scores in the study group were lower than those in the control group,and MV was higher than that in the control group(P<0.05).Conclusion:The combination of neurointerventional thrombectomy and tirofiban thrombolysis can improve the vascular recanalization rate of acute cerebral infarction and improve the function of brain nerve.

关 键 词：急性脑梗死 神经介入取栓 替罗非班 溶栓 

分 类 号：R743.3[医药卫生—神经病学与精神病学]