腹腔镜下全子宫加双附件切除术对Ⅰ期子宫内膜癌患者的疗效分析  

Analysis of the Therapeutic Effect of Laparoscopic Total Hysterectomy and Double Adnexectomy on Patients with StageⅠEndometrial Cancer

作　　者：王燕[1] 刘雪霞[1] 王社红 WANG Yan;LIU Xuexia;WANG Shehong(Zhengzhou Seventh People's Hospital,Zhengzhou,450000)

机构地区：[1]河南省郑州市第七人民医院,450000

出　　处：《实用癌症杂志》2025年第4期662-664,669,共4页The Practical Journal of Cancer

摘　　要：目的探讨腹腔镜下全子宫加双附件切除术对Ⅰ期子宫内膜癌(EC)患者的疗效。方法将85例Ⅰ期EC患者,随机划分为对照组(42例Ⅰ期EC患者)与观察组(43例Ⅰ期EC患者)。对照组行腹腔镜下广泛性全子宫切除术(LRH),观察组行腹腔镜下全子宫加双附件切除术。比较两组手术相关指标、术后恢复情况、生活质量、并发症。结果观察组术中出血量为(163.95±11.25)ml,少于对照组的(221.46±15.79)ml,手术时间为(76.30±9.70)min、住院时间为(9.79±1.61)d、术后肛门排气时间为(3.15±0.75)d、下床活动时间为(3.08±0.44)d,短于对照组[(108.52±12.54)min、(13.67±2.48)d、(5.09±1.57)d、(4.22±0.89)d],并发症发生率为4.65%(2/43),低于对照组的21.43%(9/42);且术后的癌症患者生命质量测定量表(FACT-G)内各维度评分分别为(24.02±1.94)分、(20.59±1.67)分、(24.63±1.88)分、(24.69±1.58)分,高于对照组[(20.65±1.56)分、(16.33±1.52)分、(19.75±1.63)分、(20.53±1.63)分],有统计学差异(P<0.05)。结论腹腔镜下全子宫加双附件切除术存在创伤小、并发症少等优势,可促进Ⅰ期EC患者术后恢复,提高生活质量,确保患者取得良好的预后,有利于之后手术方案的制定,值得临床借鉴。Objective To investigate the efficacy of laparoscopic total hysterectomy and double adnexectomy on patients with stage I endometrial cancer(EC).Methods 85 patients with stageⅠEC were randomly divided into the control group(42 patients with stageⅠEC)and the observation group(43 patients with stageⅠEC).The control group underwent laparoscopic radical hysterectomy(LRH),while the observation group underwent laparoscopic total hysterectomy plus bilateral adnexectomy.Compare the surgical related indicators,postoperative recovery,quality of life,and complications between the 2 groups.Results The intraoperative blood loss in the observation group was(163.95±11.25)ml,which was less than the control group's(221.46±15.79)ml.The operation time was(76.30±9.70)min,the hospital stay was(9.79±1.61)d,the postoperative anal exhaust time was(3.15±0.75)d,and the time to get out of bed was(3.08±0.44)d,which was shorter than the control group's(108.52±12.54)min,(13.67±2.48)d,(5.09±1.57)d,and(4.22±0.89)d.The incidence of complications was 4.65%(2/43),which was lower than the control group's 21.43%(9/42);The scores of each dimension in the postoperative cancer patient quality of life measurement scale(FACT-G)were(24.02±1.94)points,(20.59±1.67)points,(24.63±1.88)points,and(24.69±1.58)points,respectively,which were higher than those of the control group[(20.65±1.56)points,(16.33±1.52)points,(19.75±1.63)points,and(20.53±1.63)points](P<0.05).Conclusion laparoscopic total hysterectomy plus double adnexal resection has the advantages of less trauma and less complications,which can promote the postoperative recovery of stage I EC patients,improve the quality of life,ensure a good prognosis of patients,and is conducive to the formulation of subsequent surgical plan,which is worthy of clinical reference.

关 键 词：子宫内膜癌 Ⅰ期 生活质量 并发症 

分 类 号：R737.33[医药卫生—肿瘤]