CT对不同亚型亚实性肺腺癌的鉴别诊断价值  

Value of CT in differential diagnosis of different subtypes of subsolid lung adenocarcinoma

作　　者：康健 魏君培[1] KANG Jian;WEI Junpei(Department of Imaging,Xintai People's Hospital,Tai'an,Shandong 271200,China)

机构地区：[1]新泰市人民医院影像科,山东泰安271200

出　　处：《医药前沿》2025年第11期49-52,57,共5页Journal of Frontiers of Medicine

摘　　要：目的探讨CT对不同亚型亚实性肺腺癌的鉴别诊断价值。方法选取2022年1—12月新泰市人民医院收治的亚实性肺腺癌患者136例,收集患者的临床资料,并根据病理结果将患者分为不同亚型组,所有患者均接受CT检查。比较不同亚型组的临床资料、CT征象、平均CT值和平均病灶直径,采用多因素Logistic回归分析影响因素,并绘制受试者工作特征(ROC)曲线,对CT诊断浸润性腺癌(IA)的价值进行评估。结果136例亚实性肺腺癌患者中,浸润前病变(PL)有35例,纳入PL组;微小浸润性腺癌(MIA)有70例,纳入MIA组;IA有31例,纳入IA组。3组年龄、血管集束征出现率、胸膜凹陷征出现率、空泡征出现率、平均CT值和平均病灶直径比较,差异有统计学意义(P<0.05);多因素Logistic回归分析结果显示,平均CT值和平均病灶直径是不同亚型亚实性肺腺癌的影响因素(P<0.05);ROC曲线显示,平均CT值和平均病灶直径诊断IA的曲线下面积分别为0.752和0.809(P<0.05)。结论CT在不同亚型亚实性肺腺癌的诊断中具有重要应用价值,可通过平均CT值和平均病灶直径有效鉴别不同亚型,且对IA的诊断效能较高。Objective To investigate the value of CT in the differential diagnosis of different subtypes of subsolid lung adenocarcinoma.Methods A total of 136 patients with subsolid lung adenocarcinoma admitted to Xintai People's Hospital from January to December 2022 were selected.The clinical data of the patients were collected,and the patients were divided into different subtypes according to the pathological results.All patients underwent CT examination.The clinical data,CT signs,average CT value and average lesion diameter of different subtypes were compared.Multivariate Logistic regression analysis was used to analyze the influencing factors,and the receiver operating characteristic(ROC)curve was drawn to evaluate the value of CT in the diagnosis of invasive adenocarcinoma(IA).Results Among 136 patients with subsolid lung adenocarcinoma,there were 35 cases of preinvasive lesions(PL),which were included in the PL group;there were 70 cases of minimally invasive adenocarcinoma(MIA),which were included in the MIA group.There were 31 cases of IA included in the IA group.There were significant differences in age,occurrence rate of vascular convergence sign,occurrence rate of pleural indentation sign,occurrence rate of vacuole sign,average CT value and average lesion diameter among the three groups(P<0.05).Multivariate Logistic regression analysis showed that average CT value and average lesion diameter were the influencing factors of different subtypes of subsolid lung adenocarcinoma(P<0.05).The ROC curve showed that the area under the curve of average CT value and average lesion diameter in the diagnosis of IA was 0.752 and 0.809,respectively(P<0.05).Conclusions CT has important application value in the diagnosis of different subtypes of subsolid lung adenocarcinoma.It can effectively identify different subtypes by average CT value and average lesion diameter,and has high diagnostic efficiency for IA.

关 键 词：肺部CT平扫 亚实性肺腺癌 亚型 浸润性腺癌 鉴别诊断 LOGISTIC回归分析 

分 类 号：R734[医药卫生—肿瘤]