前沿科研成果融入应用化学专业综合实验教学——水溶性有机三价碘试剂PISA在苯丙醇氧化反应中的应用  

Integrating Frontier Scientific Research into Applied Chemistry Comprehensive Experimental Teaching:Application of Water-Soluble Hypervalent Iodine(Ⅲ)Reagent PISA in the Oxidation of Phenylpropanol

作　　者：刘姗姗 张圣燕 段永正 Liu Shanshan*;Zhang Shengyan;Duan Yongzheng(Shandong University of Aeronautics,Binzhou 256603,China)

机构地区：[1]山东航空学院,山东滨州256603

出　　处：《广东化工》2025年第6期166-168,184,共4页Guangdong Chemical Industry

基　　金：山东航空学院教学研究重点项目(BYJYZD202208);山东航空学院科研基金项目(2016Y24)。

摘　　要：本文设计了一种水溶性有机三价碘试剂的“合成、表征、应用”进阶式本科生综合实验项目。实验首先通过商品化三价碘试剂二醋酸碘酰苯与氨基磺酸反应,制备有机三价碘试剂氨基磺酸亚碘酰苯。新制备的试剂具有优异的水溶性及氧化性能,可在水溶液中高效地将苯丙醇氧化至苯丙酮。本实验可以帮助学生将有机化学理论学习中的经典反应与实践相结合,可以开拓学生的科研视野、熟悉高价碘试剂的制备及其在有机合成中的应用价值和潜力、锻炼学生有机化学实验的综合操作能力,为学生将来从事科学研究和工作奠定良好的基础。A comprehensive experimental project of undergraduate students majoring was designed for the synthesis,characterization,and its application in alcohol oxidation of a new type of water-soluble hypervalent iodine(Ⅲ)reagent.Firstly,the new hypervalent iodine(Ⅲ)reagent,aminosulfonic acid iodobenzene,was prepared through the reaction of commercialized hypervalent iodine(Ⅲ)reagent,iodobenzene diacetate,and aminosulfonic acid.The newly prepared reagent has excellent water solubility and the oxidation performance.The phenylpropanol can be oxidized to phenylacetone in aqueous solution efficiently using this reagent.The experiment can help students combine classic reactions in organic chemistry theory with practice,broaden their research horizons,familiarize the future scientific research and work.

关 键 词：科学前沿 实验教学 有机三价碘试剂 水溶性 醇氧化 

分 类 号：G642[文化科学—高等教育学]