牙髓再生支架材料的研究进展  

Research progress of scaffold materials for dental pulp regeneration

作　　者：刘塬 颜燕宏 蒋备战[1] LIU Yuan;YAN Yanhong;JIANG Beizhan(Department of Pediatric Dentistry,Shanghai Stomatological Hospital and Dental School,Tongji University&Shanghai Engineering Research Center of Tooth Restoration and Regeneration&Tongji Research Institute of Stomatology,Shanghai 200072,China)

机构地区：[1]上海市同济口腔医院儿童口腔科,同济大学口腔医学院,上海牙组织修复与再生工程技术研究中心,同济大学口腔医学研究所,上海200072

出　　处：《口腔医学》2025年第3期218-222,共5页Stomatology

基　　金：国家自然科学基金(82301012);上海市卫生健康委员会科研项目(202140357);上海申康医院发展中心新兴前沿技术联合攻关项目(SHDC12023115)。

摘　　要：牙髓再生是目前牙髓病学研究的热点课题。随着再生医学的发展,牙髓再生正从基础研究向临床应用转化,并在一些病例中观察到了比较稳定的结果,但实现更高的成功率和恢复牙髓的功能仍然是牙髓病学领域的一个挑战。干细胞、生长因子和支架材料是组织工程的基本要素。近年来牙髓再生相关支架受到广泛关注,无论是天然来源的、人体来源的还是人工合成的支架材料都取得了新的进展。该文就牙髓再生的支架材料进行综述,旨在为牙髓再生支架材料的选择提供参考。Pulp regeneration is currently a hot topic in pulp disease research.With the development of regenerative medicine,pulp regeneration is transitioning from basic research to clinical applications,and stable results have been observed in some cases.However,achieving higher success rates and restoring pulp function remains a challenge in the field of pulp disease.Stem cells,growth factors,and scaffold materials are fundamental elements of tissue engineering.In recent years,dental pulp regeneration related scaffolds have received widespread attention,and new progress has been made in natural,human,and artificially synthesized scaffold materials.This article reviews the scaffold materials for pulp regeneration,aiming to provide reference for the selection of scaffold materials for dental pulp regeneration.

关 键 词：牙髓再生 再生性牙髓治疗 干细胞 支架 

分 类 号：R781.4[医药卫生—口腔医学]