微创肺段切除术在早期非小细胞肺癌患者中的应用效果及有效性分析  

The Application Effect and Effectiveness Analysis of Minimally Invasive Lung Segmentectomy in Early Non-small Cell Lung Cancer Patients

作　　者：卫锐狮 冯利 俞建荣 赵士磊[2] 顾春东[2] WEI Ruishi;FENG Li;YU Jianrong;ZHAO Shilei;GU Chundong(Department of Thoracic Surgery,Changzhou Cancer(Fourth People′s)Hospital,Changzhou 213002,Jiangsu,China;Department of Thoracic Surgery,First Affiliated Hospital of Dalian Medical University,Dalian 116000,Liaoning,China)

机构地区：[1]常州市肿瘤(第四人民)医院胸外科,江苏常州213002 [2]大连医科大学附属第一医院胸外科,辽宁大连116000

出　　处：《系统医学》2025年第6期1-3,12,共4页Systems Medicine

基　　金：江苏省常州市“龙城医星”卫生青年科技人才托举工程项目(CYF2022007);江苏省常州市卫生健康青苗人才培养工程项目(CZQM2022019);江苏省常州市科技局应用基础研究计划项目(CJ20241026)。

摘　　要：目的分析微创肺段切除术治疗早期非小细胞肺癌(non-small cell carcinoma,NSCLC)患者的临床疗效。方法非随机选取2021年1月—2023年1月至常州市肿瘤(第四人民)医院胸外科就诊的100例NSCLC患者为研究对象,按照治疗方式的不同分为对照组(50例)与观察组(50例),对照组行单孔胸腔镜下肺叶切除术,观察组行单孔胸腔镜下肺段切除术。比较两组围术期指标、肺功能指标、并发症发生情况。结果观察组手术时间、胸腔引流量、住院时间均优于对照组,差异有统计学意义(P均<0.05);术后2个月,两组肺功能指标相比术前均有所改善,观察组第1秒用力呼气容积、用力肺活量、每分钟最大通气量分别为(1.42±0.25)L、(2.49±0.45)L、(95.32±5.92)L/min均高于对照组的(1.22±0.20)L、(2.20±0.41)L、(87.30±7.12)L/min,差异有统计学意义(t=4.417、3.368、6.124,P均<0.05)。观察组并发症发生率为2.00%(1/50),低于对照组的12.00%(6/50),差异有统计学意义(χ^(2)=3.914,P<0.05)。结论作为NSCLC的微创治疗方式,单孔入路肺段切除术在确保手术安全性的前提下,术后肺功能恢复更快,住院时间缩短,有助于改善患者康复进程。Objective To analyze the clinical effect of minimally invasive segmental resection in the treatment of early stage non-small cell carcinoma(NSCLC).Methods A total of 100 patients with NSCLC who visited the Department of Thoracic Surgery of Changzhou Cancer(the Fourth People's)Hospital from January 2021 to January 2023 were non-randomly selected as the research object.They were divided into two groups by different treatment methods.The con-trol group(50 cases)underwent single-port thoracoscopic lobectomy and the observation group(50 cases)underwent single-well thoracoscopic segmenulectomy.The perioperative indexes,pulmonary function indexes and complications were compared between the two groups.Results The operation time,thoracic drainage volume and hospital stay in the observation group were better than those in the control group,the differences were statistically significant(all P<0.05).Two months after operation,the pulmonary function indexes of the two groups were improved compared with those be-fore operation.The forced expiratory volume in one second,forced vital capacity and maximum voluntary ventilation in the observation group were(1.42±0.25)L,(2.49±0.45)L and(95.32±5.92)L/min,respectively,which were higher than(1.22±0.20)L,(2.20±0.41)L and(87.30±7.12)L/min in the control group,and the differences were statistically signifi-cant(t=4.417,3.368,6.124,all P<0.05).The incidence of complications in the observation group was 2.00%(1/50),lower than 12.00%(6/50)in the control group,and the difference was statistically significant(χ^(2)=3.914,P<0.05).Conclusion As a minimally invasive treatment for NSCLC,single-port pulmonary segmentectomy can ensure the safety of the operation,and the postoperative pulmonary function recovery is faster and the hospitalization time is shortened,which is helpful to improve the rehabilitation process of patients.

关 键 词：早期非小细胞肺癌 微创肺段切除术 应用效果 肺功能指标 

分 类 号：R734.2[医药卫生—肿瘤]