一款含2种超组装胶原成分面部精华的皮肤抗老化功效评价研究  

Evaluation study of a facial serum containing two super-assembled collagen ingredients on anti-aging efficacy

作　　者：吴黎明 温燕佳 吴田田 王长明 赵磊 WU Liming;WEN Yanjia;WU Tiantian;WANG Changming;ZHAO Lei(Xi'an Bohe Medical Technology Co.,Ltd.,Xi’an,Shaanxi 710000,China;Shaanxi Baiao Regenerative Medicine Co.,Ltd.,Xi’an,Shaanxi 710000,China;Aohe Regenerative Medicine Technology(Suzhou)Co.,Ltd.,Suzhou,Jiangsu 215500,China)

机构地区：[1]西安博和医疗科技有限公司,陕西西安710000 [2]陕西佰傲再生医学有限公司,陕西西安710000 [3]傲合再生医学科技(苏州)有限公司,江苏苏州215500

出　　处：《日用化学品科学》2025年第4期37-42,共6页Detergent & Cosmetics

摘　　要：研究一款含两种超组装胶原成分面部精华的皮肤抗老化功效。通过染色法观察离体皮肤组织中胶原纤维、Ⅰ型、Ⅲ型、Ⅳ型、ⅩⅤⅡ型胶原蛋白含量变化;基于30名自认为敏感皮肤的健康女性连续使用产品28天后,利用Primos CR仪器检测、主观问卷方式联合评估产品人体功效。体外结果显示,试验样品显著促进Ⅰ型、Ⅲ型胶原蛋白分泌(P<0.01),极其显著促进胶原纤维、Ⅳ型、ⅩⅤⅡ型胶原蛋白分泌(P<0.001);人体结果显示,在使用试验样品28天后,30名自认为敏感皮肤的健康女性鱼尾纹、眼下纹、抬头纹、紧致功效显著性改善。综上所述,含有2种超组装胶原成分精华液对皮肤老化引起的皮肤干燥、粗糙和皱纹有良好的改善效果。The anti-aging efficacy of a facial serum containing two super-assembled collagen ingredients has been studied.The contents of collagen fiber,type Ⅰ,type Ⅲ,type Ⅳ,typeⅩⅤⅡcollagen in-vitro skin tissues were observed by staining method.Based on 30 healthy women with sensitive skin who used the product continuously for 28 days,the effect of the product on human was evaluated by Primos CR instrument detection and subjective questionnaire method.In vitro results showed that the test samples significantly promoted the secretion of type Ⅰ and type Ⅲ collagen(P<0.01),and extremely significantly promoted the secretion of collagen fibers,type IV and typeⅩⅤⅡcollagen(P<0.001).Human body results showed that after 28 days of using the test samples,30 healthy women with self perceived sensitive skin showed significant improvement in crow's feet,under eye lines,forehead wrinkles,and tightening effects.In summary,the serum containing two super-assembled collagen ingredients has a good effect on improving skin dryness,roughness and wrinkles caused by skin aging.

关 键 词：超组装胶原 面部精华 胶原蛋白 抗老化 功效评价 

分 类 号：TQ658[化学工程—精细化工]