永瑞清联合聚乙二醇电解质溶液在结肠镜检查前肠道准备中的效果观察  

Observation on the effect of Yongruiqing combined with polyethylene glycol electrolyte solution in bowel preparation before colonoscopy

作　　者：沈锋[1] 潘海强[1] 包向东[1] 郁峰[1] 陈诚豪[1] 崔焌辉[1] 徐永强[2] 方晓明[3] 严杭峰 李丽军 张磊 李文春 SHEN Feng;PAN Hai-qiang;BAO Xiang-dong(Zhejiang Provincial Tongde Hospital,Hangzhou 310012,China)

机构地区：[1]浙江省立同德医院,310012 [2]湖州市第一人民医院,313000 [3]海宁市第二人民医院,314419 [4]东阳市人民医院,322100 [5]武义县第一人民医院,321200

出　　处：《中国现代药物应用》2025年第6期6-11,共6页Chinese Journal of Modern Drug Application

摘　　要：目的针对多维复合营养粉(商品名:永瑞清)联合聚乙二醇电解质溶液应用于结肠镜检查中的效果进行分析。方法选取行结肠镜检查的150例患者,根据随机数字法分为对照组、观察Ⅰ组、观察Ⅱ组,每组50例。对照组给予常规半流质低渣饮食+3 L聚乙二醇电解质溶液,观察Ⅰ组给予永瑞清+3 L聚乙二醇电解质溶液,观察Ⅱ组给予永瑞清+2 L聚乙二醇电解质溶液。对比三组患者肠道准备效果、首次排便时间、最后一次排便情况、病变检出率、肠镜到达回盲部占比、进镜时间、退镜时间、患者再次服用意愿、不良反应发生情况、检查耐受度、满意度、肠镜检查前血糖情况,并比较观察Ⅰ组和观察Ⅱ组患者的受试产品口感。结果观察Ⅰ组、观察Ⅱ组肠道准备效果优良率分别为80%、78%,均高于对照组的58%,数据之间差异存在统计学意义(P<0.05);观察Ⅰ组、观察Ⅱ组肠道准备效果优良率对比,数据之间差异不存在统计学意义(P>0.05)。观察Ⅰ组首次排便时间(18.0±1.5)min、观察Ⅱ组患者首次排便时间(22.6±1.8)min均短于对照组的(32.4±2.4)min,且观察Ⅰ组短于观察Ⅱ组,数据之间差异存在统计学意义(P<0.05)。且观察Ⅰ组、观察Ⅱ组患者最后一次排便情况均优于对照组,数据之间差异存在统计学意义(P<0.05)。观察Ⅰ组、观察Ⅱ组病变检出率分别为32%、38%,均高于对照组的16%,数据之间差异存在统计学意义(P<0.05)。三组肠镜到达回盲部占比均为100%。对照组、观察Ⅰ组、观察Ⅱ组的进镜时间分别为(8.3±0.06)、(7.2±0.05)、(6.9±0.04)min,退镜时间分别为(13.6±0.11)、(10.2±0.09)、(9.5±0.08)min,三组进镜时间、退镜时间对比,对照组更长,数据之间差异存在统计学意义(P<0.05)。观察Ⅱ组、观察Ⅰ组患者愿意再次服用占比分别为80%、50%,均高于对照组的28%,且观察Ⅱ组最高,数据之间差异存在统计学意义(P<0.05)。�Objective To analyze the effect of Multi-dimensional compound nutrient powder(trade name:Yongruiqing)combined with polyethylene glycol(PEG)electrolyte solution in bowel preparation before colonoscopy.Methods 150 patients who underwent colonoscopy were selected and divided into control group,observation groupⅠand observation groupⅡaccording to random numerical method,with 50 cases in each group.Control group was given conventional semi-fluid low residue diet+3 L polyethylene glycol electrolyte solution,observation groupⅠwas given Yongruiqing+3 L polyethylene glycol electrolyte solution,and observation groupⅡwas given Yongruiqing+2 L polyethylene glycol electrolyte solution.Comparison of effect of bowel preparation,first defecation time,last defecation time,lesion detection rate,percentage of enteroscopy reaching the ileocecal region,time of scope insertion,time of scope withdrawal,patients'willingness to take again,occurrence of adverse reactions,examination tolerance,satisfaction,and blood glucose before colonoscopy among the three groups,as well as the taste of the tested products between observation groupⅠand observation groupⅡ.Results The excellent rates of bowel preparation effect in observation groupⅠand observation groupⅡwere 80%and 78%,which were higher than 58%in control group,and the data difference was statistically significant(P<0.05);there was no statistical significance in excellent rates of bowel preparation effect between observation groupⅠand observation groupⅡ(P>0.05).The first defecation time of observation groupⅠwas(18.0±1.5)min,and the first defecation time of observation groupⅡwas(22.6±1.8)min,which was shorter than(32.4±2.4)min of control group;observation groupⅡwas shorter than observation groupⅡ;the data difference was statistically significant(P<0.05).The last defecation of observation groupⅠand observation groupⅡwas better than that of control group,and the data difference was statistically significant(P<0.05).The lesion detection rates of observation g

关 键 词：多维复合营养粉 聚乙二醇电解质溶液 肠道准备 结肠镜检查 

分 类 号：R574.62[医药卫生—消化系统]