乳腺癌术后放疗患者并发放射性肺炎的现状及危险因素分析  

Current Situation and Risk Factor Analysis of Radiation Pneumonitis in Patients Undergoing Postoperative Radiotherapy for Breast Cancer

作　　者：苏娜 崔久秀 李玉锋[1] SU Na;CUI Jiuxiu;LI Yufeng(Department of Oncology,WardⅡ,Rizhao City People’s Hospital,Rizhao 276800,China)

机构地区：[1]日照市人民医院肿瘤科二病区,山东日照276800

出　　处：《反射疗法与康复医学》2025年第5期63-65,73,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的 分析乳腺癌术后放疗患者并发放射性肺炎的现状及危险因素。方法 回顾性分析2022年1—12月日照市人民医院收治的60例乳腺癌术后放疗患者的临床资料,统计放射性肺炎的发生率,分析放射性肺炎与患者年龄、放疗天数长周期、放疗剂量、放射照射视野面积、有肺基础疾病等信息,采用Logistic回归分析影响放射性肺炎发生的危险因素。结果 60例乳腺癌术后放疗患者中发生放射性肺炎共14例,发生率为23.33%(14/60)。单因素分析结果显示,两组年龄、化疗、放疗天数、放疗剂量、放射照射视野面积、肺基础疾病比较,组间差异有统计学意义(P<0.05);多因素Logistic回归分析显示,年龄>60岁、有化疗、放疗天数长周期、放疗剂量>50 Gy、放射照射视野面积≥120 cm2、有肺基础疾病是乳腺癌术后放疗患者放射性肺炎发生的独立危险因素(P<0.05且OR>1)。结论 年龄>60岁、有化疗、放疗天数长周期、放疗剂量>50 Gy、放射照射视野面积≥120 cm2、有肺基础疾病是乳腺癌术后放疗患者放射性肺炎发生的高危因素。Objective Analysis of the current situation and risk factors of radiation pneumonitis in patients undergoing postoperative radiotherapy for breast cancer.Methods A retrospective analysis was conducted on the clinical data of 60 patients with postoperative radiotherapy for breast cancer admitted to Rizhao City People’s Hospital from January to December 2022,count the incidence of radiation pneumonitis and analyze the information such as the relationship between radiation pneumonitis and patient age,long period of radiotherapy days,radiotherapy dose,area of radiation field,and presence of underlying lung diseases,Logistic regression was used to analyze the risk factors affecting the occurrence of radiation pneumonitis.Results Among 60 patients with postoperative radiotherapy for breast cancer,radiation pneumonitis occurred in 14 cases,with an incidence rate of 23.33%(14/60),the results of univariate analysis showed that there were differences between the two groups in terms of age,chemotherapy,radiotherapy days,radiotherapy dose,area of radiation field,underlying lung diseases,and the differences between the groups were statistically significant(P<0.05);multivariate logistic regression analysis showed that age>60 years old,having chemotherapy,long period of radiotherapy days,radiotherapy dose>50 Gray,radiation field area≥120 cm2,and having underlying lung diseases were independent risk factors for the occurrence of radiation pneumonitis in patients with postoperative radiotherapy for breast cancer(P<0.05 and OR>1).Conclusion Age>60 years old,having chemotherapy,long period of radiotherapy days,radiotherapy dose>50 Gray,radiation field area≥120 cm2,and having underlying lung diseases are high-risk factors for the occurrence of radiation pneumonitis in patients with postoperative radiotherapy for breast cancer.

关 键 词：乳腺癌 术后 放射性肺炎 高危因素 

分 类 号：R737.9[医药卫生—肿瘤]