瑞芬太尼与丙泊酚复合麻醉对全麻腹腔镜结肠癌根治术患者麻醉复苏指标及认知功能的影响  

Effect of Remifentanil and Propofol Combined Anesthesia on Anesthesia Recovery Indicators and Cognitive Function in Patients Undergoing Laparoscopic Colon Cancer Radical Surgery Under General Anesthesia

作　　者：邹长玲 ZOU Changling(Department of Anesthesiology,Jinan Gangcheng District People’s Hospital,Jinan 271104,China)

机构地区：[1]济南市钢城区人民医院麻醉科,山东济南271104

出　　处：《反射疗法与康复医学》2025年第5期81-84,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的 探讨瑞芬太尼与丙泊酚复合麻醉对全麻腹腔镜结肠癌根治术患者的影响。方法 选择2023年5月—2024年5月济南市钢城区人民医院收治的72例全麻腹腔镜结肠癌根治术患者为研究对象,根据麻醉方式的不同将其分为对照组和观察组,各36例。对照组采用丙泊酚与芬太尼复合麻醉,观察组采用丙泊酚与瑞芬太尼复合麻醉。比较两组的认知功能、麻醉复苏指标、生命体征、不良反应发生情况。结果 术后2 h、4 h、6 h,观察组简易智能精神状态检查量表评分均高于对照组,组间差异有统计学意义(P<0.05)。观察组麻醉苏醒时间、自主呼吸恢复时间均短于对照组,苏醒体温高于对照组,组间差异有统计学意义(P<0.05)。麻醉10 min,观察组平均动脉压高于对照组,心率快于对照组,组间差异有统计学(P<0.05);术后10 min,观察组心率快于对照组,差异有统计学意义(P<0.05);两组平均动脉压对比,差异无统计学意义(P>0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论 在全麻腹腔镜结肠癌根治术患者中应用瑞芬太尼与丙泊酚复合麻醉,可加快患者术后认知功能的恢复,降低其对生命体征的影响,可缩短麻醉苏醒时间,有利于稳定体温,且较为安全。Objective Exploring the effect of remifentanil and propofol combined anesthesia on patients undergoing laparoscopic colon cancer radical surgery under general anesthesia.Methods A total of 72 patients who underwent laparoscopic colon cancer radical surgery under general anesthesia and were admitted to Jinan Gangcheng District People’s Hospital from May 2023 to May 2024 were selected as the research subjects,according to the different anesthesia methods,they were divided into a control group and an observation group,with 36 cases in each group.The control group was anesthetized with a combination of propofol and fentanyl,while the observation group was anesthetized with a combination of propofol and remifentanil.Compare the cognitive function,anesthesia recovery indicators,vital signs,and occurrence of adverse reactions between two groups.Results At 2 hours,4 hours,and 6 hours after surgery,the scores of the Mini-Mental State Examination in the observation group were higher than those in the control group,the differences between the groups were statistically significant(P<0.05).The recovery time of anesthesia and spontaneous breathing in the observation group were shorter than those in the control group,and the recovery body temperature was higher than that in the control group,the differences between the groups were statistically significant(P<0.05).After 10 minutes of anesthesia,the mean arterial pressure in the observation group was higher than that in the control group,and the heart rate was faster than that in the control group,and the differences between the groups were statistically significant(P<0.05);after 10 minutes of surgery,the heart rate of the observation group was faster than that of the control group,and the difference was statistically significant(P<0.05);comparison of the mean arterial pressure between the two groups,there was no statistically significant difference(P>0.05).Comparison of the incidence of adverse reactions between two groups,the difference was not statistically significant(P>0.

关 键 词：全麻腹腔镜结肠癌根治术 复合麻醉 瑞芬太尼 丙泊酚 认知功能 麻醉复苏指标 

分 类 号：R735.3[医药卫生—肿瘤]