丁苯酞联合甲磺酸倍他司汀治疗对后循环缺血性眩晕患者眩晕程度及脑血流速度的影响  

Effects of Butylphthalide Combined with Betahistine Mesylate on the Degree of Vertigo and Cerebral Blood Flow Velocity in Patients with Posterior Circulation Ischemic Vertigo

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作  者:许盈 王诚 蒋辉 XU Ying;WANG Cheng;JIANG Hui(Department of Neurology,The Third People’s Hospital of Kunshan,Kunshan 215300,China)

机构地区:[1]昆山市第三人民医院神经内科,江苏昆山215300

出  处:《反射疗法与康复医学》2025年第5期85-88,共4页Reflexology And Rehabilitation Medicine

摘  要:目的 探讨丁苯酞联合甲磺酸倍他司汀治疗后循环缺血性眩晕(PCIV)患者的临床效果。方法 选取2021年8月—2024年8月昆山市第三人民医院收治的108例PCIV患者为研究对象,按随机数字表法将其分为对照组和观察组,各54例。对照组采用甲磺酸倍他司汀治疗,观察组在对照组基础上联合丁苯酞治疗,两组均持续治疗2周。对比两组的临床疗效、眩晕程度、脑血流速度及不良反应发生情况。结果 观察组治疗总有效率为90.74%,高于对照组的70.37%,差异有统计学意义(P<0.05)。治疗后,观察组眩晕评定量表评分低于对照组,椎基底动脉、右椎动脉及左椎动脉血流速度均快于对照组,组间差异有统计学意义(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论 丁苯酞联合甲磺酸倍他司汀治疗PCIV患者疗效显著,可缓解眩晕症状,提高脑血流速度,改善后循环缺血状态,且安全性高。Objective To investigate the clinical effect of butylphthalide combined with betastine mesylate in the treatment of posterior circulation ischemic vertigo(PCIV).Methods A total of 108 PCIV patients admitted to the Third People’s Hospital of Kunshan from August 2021 to August 2024 were selected as the research objects,according to the random number table method,they were divided into a control group and an observation group,with 54 cases in each group.The control group was treated with betahistine mesylate,and the observation group was treated with butylphthalide on the basis of the control group,both groups were treated for 2 weeks.The clinical efficacy,degree of vertigo,cerebral blood flow velocity and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 90.74%,which was higher than 70.37%of the control group,and the difference was statistically significant(P<0.05).After treatment,the dizziness assessment rating scale score of the observation group was lower than that of the control group,and the blood flow velocity of the vertebrobasilar artery,right vertebral artery and left vertebral artery were faster than those of the control group,and the differences between the two groups were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Butylphthalide combined with betaustine mesylate is effective in the treatment of patients with PCIV,which can relieve vertigo,improve cerebral blood flow velocity,improve posterior circulation ischemic state,and has high safety.

关 键 词:后循环缺血性眩晕 丁苯酞 甲磺酸倍他司汀 眩晕程度 脑血流速度 

分 类 号:R743.3[医药卫生—神经病学与精神病学]

 

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