6例卵巢硬化性间质瘤病例报道并文献复习  

Report of 6 cases of ovarian sclerosing stromal tumor and literature review

作　　者：杜顺喜 寸红丽 杨宏英[1] DU Shunxi;CUN Hongli;YANG Hongying(Department of Gynecology,Yunnan Cancer Hospital/the Third Affiliated Hospital of Kunming Medical University,Kunming,650000,Yunnan,China;Radiology Department,Yunnan Cancer Hospital/the Third Affiliated Hospital of Kunming Medical University,Kunming,650000,Yunnan,China)

机构地区：[1]昆明医科大学第三附属医院/云南省肿瘤医院妇科,云南昆明650000 [2]昆明医科大学第三附属医院/云南省肿瘤医院放射科,云南昆明650000

出　　处：《肿瘤药学》2025年第1期66-71,共6页Anti-Tumor Pharmacy

摘　　要：目的探讨卵巢硬化性间质瘤(OSST)的临床病理特点,为诊疗提供参考。方法回顾分析2005年8月至2023年9月云南省肿瘤医院收治的6例经临床病理证实为OSST的病例资料,并进行文献复习。结果6例OSST患者的发病年龄为16~78岁,年龄跨度大于文献报道,其中2例为绝经后患者。1例患者因月经异常就诊,1例因腹痛就诊,3例因盆腔包块就诊,1例因其他体征就诊。6例均为单发肿瘤,且多数以左侧附件肿瘤为主。6例患者术中快速冰冻切片病理检查仅能提供形态学病理诊断,无法确定良恶性,5例患者为开腹手术,1例为微创手术。结论对于术前影像学提示实性肿瘤、未见远处转移,且肿瘤标志物水平正常的卵巢肿瘤,应考虑OSST可能。OSST预后较好,手术方式可选择微创手术,针对有生育要求的患者,可考虑充分保留生育功能。Objective To investigate the clinicopathologic features of ovarian sclerosing stromal tumor(OSST)and to provide reference for diagnosis and treatment of OSST.Methods The clinical data of six patients with OSST confirmed by clinical pathology in Yunnan Cancer Hospital from August 2005 to September 2023 were retrospectively analyzed,and the related literature was reviewed.Results The onset age of six OSST patients ranged from 16 to 78 years old,which was lon⁃ger than that reported in the literature,and even two cases were postmenopausal.One patient presented with abnormal men⁃struation,one patient presented with abdominal pain,three patients presented with pelvic mass,and one patient presented with other signs.The OSSTs of the six cases were solitary tumors,and most of them were located in the left adnexa.In the six patients,intraoperative rapid frozen section pathological examination could only provide morphologic and pathological diagnosis,but could not determine the benign or malignant nature of the tumor.Five patients underwent open surgery and one patient underwent minimally invasive surgery.Conclusion OSST should be considered for ovarian tumors with solid tumors,no distant metastasis,and normal tumor markers.OSST has a good prognosis,and minimally invasive surgery can be selected.For patients with fertility requirements,full preservation of reproductive function can be considered.

关 键 词：卵巢硬化性间质瘤 误诊 保留生育功能 

分 类 号：R737.31[医药卫生—肿瘤]