1例艾滋病合并乳腺癌患者的抗肿瘤治疗与药学监护  

The anti-tumor treatment and pharmaceutical care for a breast cancer patient with AIDS

作　　者：邓碧 杨维林 普琳梅 马翠莲 宋贤 DENG Bi;YANG Weilin;PU Linmei;MA Cuilian;SONG Xian(Department of Pharmacy,Yunnan Provincial Hospital of Infection Disease,Kunming,650000,Yunnan,China)

机构地区：[1]云南省传染病医院药剂科,云南昆明650000

出　　处：《肿瘤药学》2025年第1期118-123,共6页Anti-Tumor Pharmacy

基　　金：云南省临床医学研究中心专项(202405AJ310002)。

摘　　要：目的对1例艾滋病合并乳腺癌患者的药物治疗及药学监护过程进行分析讨论,以期为此类特殊患者的临床治疗提供参考。方法结合1例艾滋病合并乳腺癌患者化疗病例,依据循证证据,从患者抗肿瘤治疗药物剂量优化、抗HIV病毒方案调整、预防机会性感染等方面进行分析和讨论,并对患者药学监护方案提出建议。结果依据循证学结果为患者制定治疗方案,患者得到了有效的抗HIV和抗肿瘤治疗,顺利完成7个周期化疗,无明显不良反应,病情得到缓解。结论艾滋病合并乳腺癌患者治疗原则与普通肿瘤患者相同,可采用标准剂量的化疗药物进行治疗,但需加强用药监护。临床药师可在此类特殊患者的治疗中发挥专业优势,并在多学科诊疗体系中体现其价值。Objective To analyze and discuss the drug treatment and pharmaceutical care process of an AIDS patient with breast cancer,in order to provide some reference for the clinical treatment of such special patients.Methods A case of AIDS with breast cancer treated with chemotherapy was analyzed and discussed based on evidence-based medicine in terms of anti-tumor drug dosage optimization,anti-HIV regimen adjustment,prevention of opportunistic infections and so on,and suggestions for the patient's pharmaceutical care program were put forward.Results Based on the results of evidence-based treatment,the patient received effective anti-HIV and anti-tumor therapy,and successfully completed 7 cycles of chemotherapy without significant adverse effects.The patient had remission of the disease.Conclusion The treatment principle of AIDS patients with breast cancer can be the same as that of ordinary tumor patients,and they can be given standard dose of chemotherapy drugs.At the same time,medication monitoring should be done well.Clinical pharmacists can play their professional advantages in the treatment of special patients and embody their value in the multidisciplinary diagnosis and treatment.

关 键 词：艾滋病合并乳腺癌 抗肿瘤治疗 抗HIV病毒治疗 药物相互作用 药学监护 

分 类 号：R737.9[医药卫生—肿瘤] R512.91[医药卫生—临床医学] R969