血管内介入栓塞术与显微夹闭术治疗在颅内动脉瘤患者中的应用效果比较  

Comparison of the Application Effects of Endovascular Interventional Embolization and Microsurgical Clipping Endovascular in Patients with Intracranial Aneurysms

作　　者：郭林平[1] 夏令宝 GUO Linping;XIA Lingbao(Department of Neurosurgery,Shouguang People’s Hospital,Weifang 262750,China)

机构地区：[1]寿光市人民医院神经外科,山东潍坊262750

出　　处：《反射疗法与康复医学》2025年第2期105-108,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的比较血管内介入栓塞术与显微夹闭术治疗颅内动脉瘤患者的临床疗效。方法选取2022年2月—2024年4月寿光市人民医院收治的156例颅内动脉瘤患者为研究对象,根据手术方式不同将其分为显微夹闭组(n=76)和血管介入组(n=80)。比较两组的临床疗效、神经功能与日常活动能力、炎性因子水平及并发症发生情况。结果血管介入组治疗总有效率为96.25%,高于显微夹闭组的81.58%,差异有统计学意义(P<0.05)。术后1个月,血管介入组美国国立卫生研究院卒中量表评分低于显微夹闭组,改良Barthel指数评分高于显微夹闭组,组间差异有统计学意义(P<0.05)。术后48h,血管介入组血清细胞间黏附分子-1、单核细胞趋化蛋白-1水平均低于显微夹闭组,白细胞介素-10水平高于显微夹闭组,组间差异有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。结论血管内介入栓塞术治疗颅内动脉瘤的临床疗效更好,可有效改善患者的日常活动能力与神经功能,抑制炎症反应。Objective To compare the clinical efficacy of endovascular interventional embolization and microsurgical clipping in the treatment of patients with intracranial aneurysms.Methods A total of 156 patients with intracranial aneurysms admitted to Shouguang People's Hospital from February 2022 to April 2024 were selected as the research subjects,they were divided into a microsurgical clipping group(n=76)and a endovascular interventional group(n=80)according to the different surgical methods.Compare the clinical efficacy,neurological function and daily activity ability,inflammatory factor level,and occurrence of complications between the two groups.Results The total effective rate of the endovascular interventional group was 96.25%,which was higher than 81.58%of the microsurgical clipping group,and the difference was statistically significant(P<0.05).One month after surgery,the National Institutes of Health Stroke Scale score in the endovascular interventional group was lower than that in the microsurgical clipping group,and the Modified Barthel Index score was higher than that in the microsurgical clipping group,and the differences between the groups were statistically significant(P<0.05).48 hours after surgery,the serum levels of intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 in the endovascular interventional group were lower than those in the microsurgical clipping group,while interleukin-10 was higher than that in the microsurgical clipping group,and the differences between the groups were statistically significant(P<0.05).There was no statistically significant difference in the incidence of complications between the two groups(P>0.05).Conclusion Endovascular interventional embolization treatment for intracranial aneurysms has better clinical efficacy,can effectively improve the daily activity ability and neurological function of patients,and inhibit inflammatory responses.

关 键 词：颅内动脉瘤 血管内介入栓塞术 显微夹闭 细胞间黏附分子-1 单核细胞趋化蛋白-1 白细胞介素-10 

分 类 号：R742[医药卫生—神经病学与精神病学]