早产儿铁代谢与神经发育研究进展  

Research progress on iron metabolism and neurodevelopment in premature infants

作　　者：周嘉雯 陈淑坚 吴柏欣 麦钻珍 ZHOU Jia-wen;CHEN Shu-jian;WU Bo-xin;MAI Zuan-zhen(Department of Neonatology,Xiaolan People's Hospital of Zhongshan,Zhongshan Guangdong 528415,China)

机构地区：[1]中山市小榄人民医院新生儿科,广东中山528415

出　　处：《局解手术学杂志》2025年第4期363-367,共5页Journal of Regional Anatomy and Operative Surgery

基　　金：中山市卫生健康局医学科研项目(2021J328)。

摘　　要：铁是人体必需的微量元素之一,对新生儿,特别是早产儿的生长发育至关重要。其参与血红蛋白的生成,影响多种酶的活性,进而影响神经代谢、神经化学、神经解剖学以及基因/蛋白质的构成,从而对中枢神经系统的发展产生持久的影响。本文综述了近年来关于早产儿铁代谢与神经发育关系的研究进展,旨在为早产儿的临床管理和预防干预提供科学依据。Iron is one of the essential trace elements for the human body,which is crucial for the growth and development of newborns,especially premature infants.It participates in the generation of hemoglobin,affects the activity of various enzymes,and subsequently affects neurometabolism,neurochemistry,neuroanatomy,and gene/protein composition,thereby having a lasting impact on the development of the central nervous system.This article reviews the research progress on the relationship between iron metabolism and neurodevelopment in premature infants in recent years,aiming to provide scientific basis for clinical management and preventive intervention of premature infants.

关 键 词：早产儿 铁代谢 神经发育 铁补充 机制 

分 类 号：R741[医药卫生—神经病学与精神病学]