气囊辅助小肠镜在高龄小肠疾病患者中应用的安全性研究  

The safety study of balloon-assisted enteroscopy in elderly patients with small intestinal diseases

作　　者：张小朋 陈晓 李慧 于妍 孙明振 张静 宁守斌 李白容 ZHANG Xiaopeng;CHEN Xia;LI Hui;YU Yan;SUN Mingzhen;ZHANG Jing;NING Shoubin;LI Bairong(Air Force Specialty Medical Center,PLA,Depatartment of Gastroenterology,Beijing 100080,China)

机构地区：[1]中国人民解放军空军特色医学中心消化内科,100080

出　　处：《现代消化及介入诊疗》2025年第1期14-16,21,共4页Modern Interventional Diagnosis and Treatment in Gastroenterology

基　　金：首都卫生发展专项青年优才项目首发(2020-4-5123)。

摘　　要：目的 探讨气囊辅助小肠镜(Balloon-assisted enteroscopy,BAE)在高龄小肠疾病患者中应用的安全性。方法 收集空军特色医学中心2016年1月1日至2024年12月30日行无痛小肠镜检查及治疗的108例患者临床资料进行回顾性分析。按年龄分为高龄组(≥75岁)和非高龄组(<75岁),其中高龄组54例,按同一操作者及同性别,以1∶1配比选取同时期非高龄成年患者54例作为对照,对比分析两组患者的临床资料、受检病因、病变检出率、镜下治疗率及相关并发症情况。结果 高龄组患者合并慢性疾病率及美国麻醉医协会(American society of Aneshesiologists,ASA)评分均高于非高龄组(χ^(2)=11.80,P=0.001;χ^(2)=19.88,P<0.001),差异具有统计学意义;其余基线特征进镜途径、进镜深度及进镜时间相比,均无统计学差异(χ^(2)=1.65,P=0.439;t=-0.18,P=0.418;t=-0.42,P=0.411);两组患者主要的受检病因均为不明原因消化道出血,发生率相比较差异无统计学意义(χ^(2)=0.61,P=0.433);两组患者疾病检出率及镜下治疗率比较,均无统计学差异(χ^(2)=0.00,P=1.000;χ^(2)=1.50,P=0.221);高龄组患者术后并发症发生率与非高龄组比较,差异无统计学意义(χ^(2)=3.09,P=0.079)。结论 BAE对小肠疾病诊断具有重要价值,且在高龄患者中行BAE检查及治疗具有良好的安全性。Objective To investigate the safety of balloon-assisted enteroscopy(BAE)in elderly patients with small intestinal diseases.Methods The clinical data of 82 patients who underwent painless enteroscopy and treatment in Air Force Medical Center from January 1,2016 to December 30,2024 were retrospectively analyzed.They were divided into the senior group(≥75 years old)and the non-senior group(<75 years old),of which 54 cases were in the senior group.According to the same operator and the same sex,54 non-elderly adult patients of the same period were selected as controls with 1:1 ratio.The clinical data,etiology,detection rate of lesions,treatment rate under microscope and related complications of the two groups were compared and analyzed.Results The rate of combined underlying diseases and the score of American society of Aneshesiologists(ASA)in the elderly group were higher than those in the non-elderly group,with statistical significance( χ~2=11.80,P=0.001;χ~2=19.88,P<0.001).There were no statistically significant differences in other baseline characteristics,such as entry path,entry depth and entry time( χ~2=1.65,P=0.439;t=-0.18,P=0.529;t=-0.42,P=0.411).The main cause of gastrointestinal bleeding was unknown,and there was no significant difference in incidence between the two groups( χ~2=0.61,P=0.433).There were no significant differences in disease detection rate and treatment rate under microscope between the two groups( χ~2=0.00,P=1.000;χ~2=1.50,P=0.221).There was no significant difference in the incidence of postoperative complications between the elderly group and the non-elderly group( χ~2=3.09,P=0.079).Conclusion BAE is of great value in the diagnosis of small intestine diseases.In addition,BAE examination and treatment in elderly patients have good safety.

关 键 词：气囊辅助小肠镜 小肠疾病 高龄 安全性 

分 类 号：R574[医药卫生—消化系统]