Adding new dimension to non-directed C(sp^(3))-H functionalizations  

作　　者：Konstantin P.Bryliakov 

机构地区：[1]Laboratory of Selective Oxidation Catalysis,N.D.Zelinsky Institute of Organic Chemistry RAS,Moscow 119991,Russia

出　　处：《Science China Chemistry》2025年第4期1215-1217,共3页中国科学(化学英文版)

摘　　要：Aliphatic C-H groups are among the most abundant yet least reactive functional groups in organic molecules.Nature has evolved metalloenzymes such as those of the cytochrome P450 superfamily that efficiently activate individual tertiary(3)and secondary(2)C(sp^(3))-H bonds in complex molecules with the highest level of regio-and stereoselectivity[1];thus encouraging studies aimed at engineering artificial metalloenzymes for synthetic applications[2].

关 键 词：complex molecules organic moleculesnature aliphatic c h groups METALLOENZYMES non directed c sp h functionalization synthetic applications cytochrome p cytochrome p superfamily 

分 类 号：O621.3[理学—有机化学]