系统性红斑狼疮患者心身共病关系的潜在类别分析  

Latent class analysis of psychosomatic comorbidity relationships in patients with systemic lupus erythematosus

作　　者：刘晓潼 卢燕娥 王晓[2] 刘佳佳 LIU Xiaotong;LU Yan′e;WANG Xiao;LIU Jiajia(School of Nursing,Peking University,Beijing 100191,China;Department of Rheumatology,Qilu Hospital of Shandong University,Jinan 250063,China)

机构地区：[1]北京大学护理学院,北京100191 [2]山东大学齐鲁医院风湿科,济南250063

出　　处：《中国心理卫生杂志》2025年第5期405-410,共6页Chinese Mental Health Journal

基　　金：2023年山东省医学会青年人才托举工程资助(2023_LC_0129)。

摘　　要：目的:探索系统性红斑狼疮(SLE)患者心理健康问题的潜在类别,分析其与患者疾病活动度以及疲劳的关联性。方法:选取2022年2月-2023年12月于山东大学齐鲁医院风湿科就诊的SLE患者147名。采用潜在类别分析探索心理健康问题的潜在类别,通过多元线性回归分析SLE患者心理健康问题的潜在类别与患者疾病活动度和疲劳的关联性。结果:将SLE患者的心理健康问题分为2个潜在类别,高心理健康问题组(n=60)和低心理健康问题组(n=87)。与低心理健康问题组相比,高心理健康问题组与患者自评疾病活动度(β=0.22)和疲劳(β=0.27)正关联。结论:SLE患者心理健康问题常常同时发生,在进行心理干预时应选择综合的管理策略。Objective:To explore the latent categories of mental health problems in patients with systemic lupus erythematosus(SLE)through latent class analysis,and to analyze the association between these mental health categories and both disease activity and fatigue in patients.Methods:Totally 147 patients with SLE were recruited from February 2022,to December 2023,at the department of Rheumatology,Qilu Hospital of Shandong University.Latent class analysis was utilized to identify the latent categories of mental health problems.Multivariate linear regression was employed to analyze the association between these mental health categories and both disease activity and fatigue in patients with SLE.Results:Latent class analysis of four types of mental health problems in patients with SLE revealed two latent categories:a high mental health problems group(n=60)and a low mental health problems group(n=87).Compared to the low mental health problems group,the high mental health problems group showed a positive association with patient self-assessed disease activity(β=0.22)and fatigue(β=0.27).Conclusion:Mental health problems are common among patients with SLE and occur concurrently.Comprehensive management strategies should be selected when implementing psychological interventions.

关 键 词：系统性红斑狼疮 心理健康 疾病活动度 疲劳 潜在类别分析 

分 类 号：R749.2[医药卫生—神经病学与精神病学] R593.24[医药卫生—临床医学]