单操作孔电视胸腔镜手术与传统开胸手术治疗非小细胞肺癌患者临床分析  

Clinical analysis of single-operating hole TV thoracoscopic surgery and traditional open-heart surgery in the treatment of non-small cell lung cancer patients

作　　者：韩玉杰 Han Yujie(Department of Trauma Surgery,Zhengzhou Central Hospital,Zhengzhou 450000,China)

机构地区：[1]郑州市中心医院创伤外科病区,郑州450000

出　　处：《实用医技杂志》2025年第3期228-231,共4页Journal of Practical Medical Techniques

摘　　要：目的对比分析单操作孔电视胸腔镜手术、传统开胸手术在非小细胞肺癌中的效果。方法选择2021年4月至2024年1月郑州市中心医院胸外科接诊的91例非小细胞肺癌患者,根据手术方式分为试验组(46例)和对照组(45例)。对照组予以传统开胸手术,试验组予以单操作孔电视胸腔镜手术。对比2组手术总用时等围术期情况、术后不同时点疼痛感[视觉模拟评分(VAS)评分]、手术前后炎症指标[白细胞介素-6(IL-6)、C反应蛋白(CRP)、白细胞介素-2受体(IL-2R)]、术后不良反应。结果与对照组相比,试验组手术总用时、切口长度、留置引流管时间、住院时间更短(t=-2.938、-18.202、-3.610、-8.208,P=0.004、<0.001、0.001、<0.001),术中出血总量更低(t=-3.460,P=0.001);2组淋巴结清扫量对比,差异无统计学意义(P>0.05);术后6 h、术后12 h、术后24 h、术后36 h、术后48 h,试验组VAS评分较对照组更低(t=-4.492、-3.497、-3.623、-4.937、-5.689,P<0.001、0.001、0.001、<0.001、<0.001);试验组术后IL-6、IL-2R、CRP均比对照组低(t=-9.198,-8.248,-6.743,P均<0.001);与对照组术后不良反应发生率(22.2%)相比,试验组(6.7%)更低(χ^(2)=4.406,P=0.036)。结论与传统开胸手术相比,单操作孔电视胸腔镜手术治疗非小细胞肺癌具有创面小、术中出血量少、术后患者痛感轻等优点,且单操作孔电视胸腔镜手术对机体炎症指标的影响更小,术后不良反应发生风险亦更低。Objective To compare and analyze the effect of single-operated hole TV thoracoscopic surgery,traditional open thoracic surgery in non-small cell lung cancer.Methods Ninty-one cases of non-small cell lung cancer patients received by the Department of Thoracic Surgery of the Zhengzhou Central Hospital where we were located from April 2021 to January 2024 were selected and divided into the experimental group(46 cases)and the control group(45 cases)according to operation method.The control group was subjected to traditional open thoracic surgery,and the experimental group was subjected to single-operation hole TV thoraco-scopic surgery.The two groups were compared in terms of total operation time and other perioperative conditions,postoperative pain at different time points(VAS score),pre-and postoperative inflammatory indicators[interleukin-6(IL-6),C-reactive protein(CRP),interleukin-2 receptor(IL-2R)],and postoperative adverse reactions.Results Compared with the control group,the total operation time,incision length,catheter indwelling time and hospital stay of the experimental group were shorter(t=-2.938、-18.202、-3.610、-8.208,P=0.004、<0.001、0.001、<0.001).The total amount of intraoperative bleeding was lower(t=-3.460,P=0.001).There was no significant difference in lymph node dissection between the two groups(P>0.05).After 6 h,12 h,24 h after operation,postoperative postoperative 36 h,48 h postoperatively,patients lower VAS score(t=4.492、3.497、3.623、4.937、5.689,P<0.001、0.001、0.001、<0.001、<0.001);IL-6,IL-2R and CRP in experimental group were lower than those in control group(t=-9.198,-8.248,-6.743,all P<0.001).The incidence of postoperative adverse reactions in experimental group(6.7%)was lower than that in control group(22.2%)(χ^(2)=4.406,P=0.036).Conclusion Compared with traditional thoracotomy,video-assisted thoracoscopic surgery with single operating-hole has the advantages of smaller wound surface,less intraoperative blood loss,and less postoperative pain.Moreover,video-assisted thor

关 键 词：癌 非小细胞肺 单操作孔电视胸腔镜手术 开胸手术 

分 类 号：R734.2[医药卫生—肿瘤]