数字化钛网与可吸收性胶原膜骨增量效果的对比——一项回顾性研究  

Comparison of bone augmentation effects between digital titanium mesh and resorbable collagen membrane:a retrospective study

作　　者：李松航 蔡潇潇[1] Li Songhang;Cai Xiaoxiao(State Key Laboratory of Oral Diseases,National Clinical Research Center for Oral Diseases,Department of Oral Implantology,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,Sichuan,China)

机构地区：[1]口腔疾病研究国家重点实验室、国家口腔疾病临床医学研究中心、四川大学华西口腔医院种植科,成都610041

出　　处：《中国口腔种植学杂志》2025年第1期19-26,共8页Chinese Journal of Oral Implantology

基　　金：国家自然科学基金(82322015、82401189);四川大学华西口腔医院探索与研发项目(LCYJ2020-DC-1);国家资助博士后人员计划(GZB20230468);四川省自然科学基金(2025ZNSFSC0748)。

摘　　要：目的对比评估数字化钛网与可吸收性胶原膜在骨增量后的临床效果。方法回顾性收集2019年1月至2020年12月于四川大学华西口腔医院种植科就诊的Terheyden 2/4或3/4型骨缺损患者24例,并将其分为可吸收性胶原膜组(12例)和数字化钛网组(12例)。2组患者分别在引导骨再生阶段采用了可吸收性胶原膜和数字化钛网作为屏障。在术前(T_(1))、术后(T_(2))、二期手术前(T_(3))及负荷后1年(T_(4))对患者的牙槽骨进行二维和三维水平的测量分析,从而对硬组织稳定性进行评估。结果可吸收性胶原膜组及数字化钛网组均能够在术后达到出色的骨增量效果,可吸收性胶原膜组在术后平均单牙位骨增量354.43 mm^(3)(330.04,403.93),数字化钛网组则在术后获得了368.98 mm^(3)(320.90,441.61)骨增量。尽管在术后可吸收性胶原膜组唇侧骨板均厚于数字化钛网组,然而在经过愈合期及负荷期后,数字化钛网组在唇侧骨板各位点厚于可吸收性胶原膜组。不论是在短期愈合还是长期行使功能后,数字化钛网组的唇舌侧骨板吸收量均要小于可吸收性胶原膜组。除此之外,在三维体积上,负荷1年后,数字化钛网组牙槽骨平均吸收154.83 mm^(3)(142.65,178.76),可吸收性胶原膜组平均单牙位吸收量207.18 mm^(3)(184.94,256.44),存在统计学差异,数字化钛网表现出了出色的骨保存结果。结论数字化钛网的骨增量效果更好,其能够通过在早期愈合阶段维持稳定的成骨空间,并对负荷后产生积极影响。Objective To evaluate the clinical outcomes of bone augmentation using digital titanium mesh versus absorbable collagen membrane.Methods From January 2019 to December 2020,24 patients with Terheyden type 2/4 or 3/4 bone defects were treated at the Department of Oral Implantology,West China Hospital of Stomatology.These patients were divided into two groups:the absorbable collagen membrane group(12 cases)and digital titanium mesh group(12 cases).Both groups underwent guided bone regeneration with absorbable collagen membrane and digital titanium mesh as barrier membranes,respectively.The two-dimensional and three-dimensional measurements of alveolar bone were taken at four time points:pre-surgery(T_(1)),post-surgery(T_(2)),before second-stage surgery(T_(3)),and one year after loading(T_(4)),to evaluate hard tissue stability.Results Both the absorbable collagen membrane group and the digital titanium mesh group achieved excellent bone augmentation outcomes after surgery.The average single-tooth augmentation was 354.43 mm^(3)(330.04,403.93)in the absorbable membrane group,and in the digital titanium mesh group,it was 368.98 mm^(3)(320.90,441.61).Although the labial bone in the absorbable collagen membrane group was thicker than in the digital titanium mesh group at T_(2),after the healing and loading periods,the digital titanium mesh group exhibited thicker labial bone at all measurement points.Both in the short-term healing and long-term functional phases,the resorption of the labiolingual bone in the digital titanium mesh group was lower than in the absorbable collagen membrane group.Additionally,the digital titanium mesh group showed superior bone preservation results in terms of three-dimensional volume.Conclusion Digital titanium mesh offers superior bone augmentation effects compared to absorbable collagen membranes.It maintains a stable osteogenic space during the early healing phase and exerts a positive influence during the loading phase.

关 键 词：钛网 引导骨再生 可吸收性胶原膜 骨增量 

分 类 号：R783.6[医药卫生—口腔医学]