钛网辅助引导骨再生下假骨膜的研究进展  

Progress in pseudo-periosteum formation under titanium mesh assisted guided bone regeneration

作　　者：杨敏雪 李帝泽 陈陶 Yang Minxue;Li Dize;Chen Tao(Stomatological Hospital of Chongqing Medical University,Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences,Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education,Chongqing 401147,China)

机构地区：[1]重庆医科大学附属口腔医院、口腔疾病与生物医学重庆市重点实验室、重庆市高校市级口腔生物医学工程重点实验室,401147

出　　处：《中国口腔种植学杂志》2025年第1期35-39,共5页Chinese Journal of Oral Implantology

基　　金：重庆英才创新创业领军人才项目(CQYC20220303655);未来医学青年创新团队发展支持计划项目(W0077)。

摘　　要：在处理复杂牙槽骨缺损时,钛网作为不可吸收性屏障膜代表之一,其关键作用在于空间维持。在钛网植入术后,新骨表面常形成一层致密的纤维结缔组织——假骨膜,根据其厚度可分为3种类型。假骨膜的形成与钛网的使用紧密相关,即便是3D打印个性化钛网,其形成依然无法避免。假骨膜形成的影响因素尚未明确,可能与钛网微动、孔隙大小等因素有关。在临床应用中,假骨膜在软组织增量和新骨保护方面有一定价值,但部分学者认为其会占据成骨空间,保留与否尚存争议。目前,假骨膜的形成机制、解剖组织学特征、临床应用价值及其留存争议尚未得到全面系统阐释。本综述将综合剖析钛网下假骨膜的形成、组织结构学特点、临床应用及其留存争议,以期为临床实践提供指导和参考。In addressing complex bone defects,titanium mesh,as one of the non-absorbable barrier membranes,plays a key role in space maintenance.After surgery,a dense fibrous connective tissue,known as pseudo-periosteum,often forms on the surface of the newly formed bone.This tissue can be categorized into three types based on its thickness.The formation of the pseudo-periosteum is closely associated with the use of titanium mesh,and its formation remains unavoidable even with the use of 3D printing individualized titanium mesh.The factors influencing the formation of the pseudo-periosteum are not yet fully understood,but may be include variables such as micromotion of the titanium mesh and pore size.In clinical applications,the pseudo-periosteum has certain value in soft tissue augmentation and protection of new bone,but some researchers argue that it may occupy bone-forming space,and whether it should be retained remains controversial.Currently,the formation mechanism,anatomical and histological characteristics,clinical value,and retention controversies of the pseudo-periosteum have not been comprehensively and systematically elucidated.This review aims to provide a comprehensive analysis of the formation,histological characteristics,clinical applications,and retention controversies of the pseudo-periosteum under titanium mesh,with the goal of offering guidance and reference for clinical practice.

关 键 词：牙槽骨增量 钛网 假骨膜 纤维结缔组织 

分 类 号：R783.6[医药卫生—口腔医学]