Psychological effects of virtual reality intervention on breast cancer patients with different personalities: A randomized controlled trial  

虚拟现实干预对不同人格乳腺癌患者心理影响的随机对照试验

作　　者：Shanshan Wu Guodu Liu Jie Yang Xinxin Xie Mei-E Wu Lili Wang Yanhui Zhang Jinmei Chen Xiaowei Wang Wanjiao Li Yihong Qiu Jie Chen 伍珊珊;刘国都;杨捷;谢欣欣;吴美娥;王丽丽;张艳慧;陈锦妹;王小卫;李万娇;邱逸红;陈洁

机构地区：[1]Deparment of Oncology,Sun Yat-Sen Memorial Hospital,Sun Yat-Sen University,Guangzhou,Guangdong,China [2]Department of Cardiology,The Eighth Afliated Hospital oint Laboratory of Guangdong-Hong Kong-Macao Universities for Nutritional Metabolism and Precise Prevention and Control of Major Chronic Diseases,Sun Yat-Sen University,Shenzhen,Guangdong,China [3]Department of Breast,Sun Yat-Sen Memorial Hospital,Sun Yat-Sen University,Guangzhou,Guangdong,China [4]Deparment of Radiotherapy,Sun Yat-Sen Memorial Hospita,Sun Yat-Sen Univrsity,Guangzhou,Guangdong,China [5]Department of Nursing,Sun Yat-Sen Memorial Hospital,Sun Yat-Sen University,Guangzhou,Guangdong,China

出　　处：《International Journal of Nursing Sciences》2025年第2期107-114,共8页国际护理科学(英文)

基　　金：supported by a project of the National Natural Science Foundation of China:Research on the integration of artificial intelligence and virtual reality technology to promote psychological rehabilitation of breast cancer patients with different personalities(project approval no.82073408).

摘　　要：Objectives:To explore the efficacy and safety of virtual reality(VR)in relieving negative emotions in patients with breast cancer with different personalities.Methods:A randomized controlled trial was conducted.Between April 2023 and October 2023,we enrolled patients with breast cancer treated in the Department of Breast Cancer and Oncology at Sun Yat-Sen Memorial Hospital,Sun Yat-Sen University,Guangdong Province.The patients were randomly divided into an intervention group(n=118)and a control group(n=119)using block randomization.The intervention group received the VR intervention 3-5 times over 5±2 weeks using natural landscapes with music or relaxation guidance,and the duration of each VR intervention was 15±3 min.The control group received routine nursing care,including disease education and psychological counseling.Patients were assessed using the Type D Scale,Positive and Negative Affect Scale,and Distress Thermometer,and adverse events during the intervention were recorded.Results:Overall,85 patients completed the study(44 in the intervention group and 41 in the control group).Patients with Type D personalities showed more negative emotions[25.0(21.5,27.5)vs.19.0(16.0,24.0),P=0.001]and distressed attitudes[4.0(2.0,5.0)vs.3.0(1.0,4.0),P=0.020]with fewer positive emotions(27.2±5.6 vs.31.0±5.9,P=0.014)than those with non-Type D personalities.Total population analysis revealed no significant differences between the groups.However,in the subgroup analysis,patients with Type D personalities in the intervention group showed greater relief from negative emotions than those in the control group[median difference,-5.0(-9.0,-2.5)vs.-2.0(-4.0,2.0),P=0.046].No significant differences were found between groups of patients with non-Type D personality traits.The proportion of adverse events was not significantly different between groups(P=0.110).Conclusions:Breast cancer patients with Type D personalities suffer more severe negative emotions and distress,and more attention should be paid to them.VR intervention signi目的探讨虚拟现实(virtual reality,VR)技术对于缓解不同人格乳腺癌患者负面情绪的有效性和安全性。方法于2023年4月至10月,选取中山大学孙逸仙纪念医院乳腺科及肿瘤科的乳腺癌患者为研究对象,采用区组随机法将患者随机分为干预组和对照组。干预组患者在常规护理措施基础上,5±2周时间内接受3~5次VR技术干预,每次干预时间为15±3min,干预措施为自然景观视频配合音乐、放松引导语。对照组接受常规护理措施,主要包括疾病知识宣教和心理疏导。采用D型人格量表、正负性情绪量表、心理痛苦温度计对患者进行调查,并记录干预过程中的不良反应。结果最终85例患者完成研究(干预组44例,对照组41例)。与非D型人格患者相比,D型人格患者表现出更严重的负极情绪[25.0(21.5,27.5)比19.0(16.0,24.0),P=0.001]和心理痛苦[4.0(2.0,5.0)比3.0(1.0,4.0),P=0.020],积极情绪更少[(27.2±5.6)比(31.0±5.9),P=0.014]。虽然干预后总人群分析发现两组间没有显著差异,但在亚组分析发现,VR组D型人格患者的负性情绪缓解程度优于对照组[中位差值,-5.0(-9.0,-2.5)比-2.0(-4.0,2.0),P=0.046],非D型人格患者组间比较,差异无统计学意义。两组间不良事件发生率比较,差异无统计学意义(P=0.110)。结论D型人格乳腺癌患者负性情绪和心理痛苦更严重,需要加强关注,VR干预可有效且安全地降低D型人格患者的负向情绪。

关 键 词：Breast neoplasms Rehabilitation research Randomized controlled trial Type D personality Virtual reality 

分 类 号：R737.9[医药卫生—肿瘤]