肠道菌群失调与肝硬化并发自发性腹膜炎的关系及国内外中西医预防治疗现状  

Relationship between intestinal flora disturbance and cirrhosis complicated with SBP and the prevention and treatment status of TCM and western medicine

作　　者：陈谦 谢冬梅 麻飞玲 黄灵跃 徐美娟 何琦 Chen Qian;Xie Dongmei;Ma Feiling;Huang Lingyue;Xu Meijuan;He Qi(Department of Pharmacy,Yongjia Traditional Chinese Medical Hospital,Wenzhou,Zhejiang 325100,China;Department of Liver and Infectious Disease,Yongjia Traditional Chinese Medical Hospital,Wenzhou,Zhejiang 325100,China)

机构地区：[1]永嘉县中医医院药剂科,浙江温州325100 [2]永嘉县中医医院肝病感染科,浙江温州325100

出　　处：《中国药物与临床》2025年第7期463-469,共7页Chinese Remedies & Clinics

基　　金：浙江省温州市医药卫生科学研究项目(Z2023022)。

摘　　要：从肠道菌群探讨治疗肝硬化并发自发性腹膜炎(SBP)及相关机制研究提供相应的理论基础,为肝硬化并发SBP的临床预防治疗提供新的思路。不管从中医还是西医角度,肠道菌群与肝硬化并发SBP的发生、发展密切相关。治疗方法从中药内服、外用、灌肠,到国际上较新的粪菌移植,中西药结合纠正肠道菌群失调或将成为预防和治疗肝硬化并发SBP的新方向和新靶点。This study explores the therapeutic potential of targeting intestinal flora for liver cirrhosis complicated by spontaneous bacterial peritonitis(SBP)and investigates the underlying mechanisms,providing a theoretical foundation for clinical prevention and treatment.From both traditional chinese medicine(TCM)and western medicine perspectives,intestinal flora is closely associated with the onset and progression of SBP in liver cirrhosis.Treatment approaches range from oral and topical herbal medicine,enema therapy,to advanced international techniques such as fecal microbiota transplantation(FMT).The integration of chinese and western medicine to correct intestinal dysbiosis may emerge as a novel strategy and therapeutic target for the prevention and management of SBP in liver cirrhosis.

关 键 词：胃肠道微生物组 腹膜炎 肝硬化 中西医关系 

分 类 号：R575.2[医药卫生—消化系统]